A New Flow-Diverter (the FloWise): In-Vivo Evaluation in an Elastase-Induced Rabbit Aneurysm Model

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Byung Moon KimDong Ik Kim

Abstract

We aimed to evaluate the efficacy and safety of a newly developed, partially retrievable flow-diverter (the FloWise) in an elastase-induced rabbit aneurysm model. We developed a partially retrievable flow diverter composed of 48 strands of Nitinol and platinum wire. The FloWise is compatible with any microcatheter of 0.027-inch inner diameter, and is retrievable up to 70% deployment. The efficacy and safety of the FloWise were evaluated in the elastase-induced rabbit aneurysm model. The rate of technical success (full coverage of aneurysm neck) and assessment of aneurysm occlusion and stent patency was conducted by angiograms and histologic examinations at the 1-month, 3-month, and 6-month follow-up. The patency of small arterial branches (intercostal or lumbar arteries) covered by the FloWise were also assessed in the 5 subjects. We attempted FloWise insertion in a total of 32 aneurysm models. FloWise placement was successful in 31 subjects (96.9%). Two stents (6.2%) were occluded at the 3-month follow-up, but there was no evidence of in-stent stenosis in other subjects. All stented aneurysms showed progressive occlusion: grade I (complete aneurysm occlusion) in 44.4% and grade II (aneurysm occlusion > 90%) in 55.6% at 1 month...Continue Reading

References

May 30, 2003·Neuroradiology·Timo KringsArmin Thron
Jul 7, 2007·Stroke; a Journal of Cerebral Circulation·David F KallmesHarry J Cloft
Apr 17, 2009·AJNR. American Journal of Neuroradiology·D F KallmesH J Cloft
Jan 17, 2013·Stroke; a Journal of Cerebral Circulation·Waleed BrinjikjiDavid F Kallmes

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Citations

Jun 2, 2017·Neurosurgical Focus·Gary RajahLeonardo Rangel-Castilla
Mar 29, 2019·Neuroradiology·Tiffany W ShenKristen O'Halloran Cardinal
Sep 2, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yongxin ZhangJianmin Liu
Jun 4, 2020·Journal of Neurointerventional Surgery·Kapilan PanchendraboseAlim P Mitha
Jun 4, 2020·Journal of Neurointerventional Surgery·Frederik FriesRuben Mühl-Benninghaus
Feb 26, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Byung Moon KimDong Ik Kim
May 15, 2021·Journal of Neurointerventional Surgery·Clemens HufnaglMonika Killer-Oberpfalzer

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Software Mentioned

FloWise
SPSS

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Aneurysm

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