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A new HLA map of Europe: Regional genetic variation and its implication for peopling history, disease-association studies and tissue transplantation

Human Heredity

May 21, 2014

Alicia SANCHEZ-MAZASJosé Manuel Nunes

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Abstract

HLA genes are highly polymorphic in human populations as a result of diversifying selection related to their immune function. However, HLA geographic variation worldwide suggests that demographic factors also shaped their evolution. We here analyzed in detail HLA genetic variation in Eu...read more

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  • A new HLA map of Europe: Regional genetic variation and its implication for peopling history, disease-association studies and tissue transplantation

    Human Heredity

    May 21, 2014

    Alicia SANCHEZ-MAZASJosé Manuel Nunes

    PMID: 24861861

    DOI: 10.1159/000360855

    Abstract

    HLA genes are highly polymorphic in human populations as a result of diversifying selection related to their immune function. However, HLA geographic variation worldwide suggests that demographic factors also shaped their evolution. We here analyzed in detail HLA genetic variation in Eu...read more

    Paper Details
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    • Citations14

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    • References
    • Citations14
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