A new indication for an intracytoplasmic sperm injection procedure outside the cases of severe male factor infertility

European Journal of Obstetrics, Gynecology, and Reproductive Biology
M LudwigK Diedrich

Abstract

To show the success of intracytoplasmic sperm injection (ICSI) in cases of a low number of oocytes retrieved. 715 microinjection cycles, which were performed at our center, were analyzed retrospectively. Within the analyzed cycles, there were 50 cycles with less than four oocytes retrieved. Twelve, 18, and 20 cases were treated with one, two, and three oocytes, respectively. The rate of metaphase II oocytes injected and subsequently fertilized, and intact oocytes was similar in the three groups. The transfer rate was not significantly different from those cases with more than three oocytes (84% vs. 94%). Therefore, the rate of fertilization failure was not higher in the low-number group. The number of embryos transferred was statistically significantly lower in the group with one and two oocytes compared to the group with three oocytes (1, and 1.31 vs. 2.27; P < 0.01) and the group of all patients (2.63; P < 0.01), as well as between the group of less than four oocytes and all patients (1.63 vs. 2.63; P < 0.01). There was no statistically significant difference between the pregnancy rates of the three groups (36.4% vs. 20% vs. 22.2%), and also no difference was found between the group with less than four oocytes and the data of...Continue Reading

References

May 1, 1993·Geburtshilfe und Frauenheilkunde·S AlpüstünD Krebs

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Citations

Jul 28, 2011·Journal of Assisted Reproduction and Genetics·Martha LunaAlan B Copperman
Oct 1, 2013·Journal of Assisted Reproduction and Genetics·Ermanno GrecoMaria Giulia Minasi
Jul 14, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·N NikolettosK Diedrich
Dec 1, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·M LudwigK Diedrich
Jan 13, 2004·Journal of Assisted Reproduction and Genetics·Sozos J FasouliotisAlex Simon
Aug 29, 2009·Reproductive Biomedicine Online·Andrea BoriniMonica Cattoli
Sep 6, 2012·Journal of Zhejiang University. Science. B·Qing-song XiHan-wang Zhang
Sep 21, 2010·Systems Biology in Reproductive Medicine·Roberta MaggiulliGianpiero D Palermo

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