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A new insight for the screening of potential ?-lactamase inhibitors

bioRxiv

May 14, 2014

Vijai Singh, Dharmendra Kumar Chaudhary

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Abstract

The ?-lactamase produces by Aeromonas hydrophila which enables to hydrolyze and inactivate ?-lactam ring of antibiotics. The homology modeling was used to generate the 3-D model of ?-lactamase by using known template 3-D structure. The stereochemical quality and torsion angle of 3-D mod...read more

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Beta-Lactamase
Amino Acid [EPC]
Lactams
Homologous Gene
Antibiotic throat preparations
Antibiotics, ophthalmologic
Antifungal Antibiotics, Topical
Ampicillin
Lactamase
Structure
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  • A new insight for the screening of potential ?-lactamase inhibitors

    bioRxiv

    May 14, 2014

    Vijai Singh, Dharmendra Kumar Chaudhary

    PMID: 990005181

    DOI: 10.1101/005181

    Abstract

    The ?-lactamase produces by Aeromonas hydrophila which enables to hydrolyze and inactivate ?-lactam ring of antibiotics. The homology modeling was used to generate the 3-D model of ?-lactamase by using known template 3-D structure. The stereochemical quality and torsion angle of 3-D mod...read more

    Mentioned in this Paper

    Beta-Lactamase
    Amino Acid [EPC]
    Lactams
    Homologous Gene
    Antibiotic throat preparations

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