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A new insight for the screening of potential β-lactamase inhibitors

bioRxiv

May 14, 2014

Vijai Singh, Dharmendra Kumar Chaudhary

Abstract

The β-lactamase produces by Aeromonas hydrophila which enables to hydrolyze and inactivate β- lactam ring of antibiotics. The homology modeling was used to generate the 3-D model of β-lactamase by using known template 3-D structure. The stereochemical quality and torsion angle of 3-D mo...read more

Mentioned in this Paper

Homology Modeling
Docking -molecular Interaction
Ampicillin
Lactams
Screening Generic
Monobactams
Antibiotics
Antibiotics, Antitubercular
beta-Lactams
beta-Lactamase Inhibitors
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A new insight for the screening of potential β-lactamase inhibitors

bioRxiv

May 14, 2014

Vijai Singh, Dharmendra Kumar Chaudhary

PMID: 990005181

DOI: 10.1101/005181

Abstract

The β-lactamase produces by Aeromonas hydrophila which enables to hydrolyze and inactivate β- lactam ring of antibiotics. The homology modeling was used to generate the 3-D model of β-lactamase by using known template 3-D structure. The stereochemical quality and torsion angle of 3-D mo...read more

Mentioned in this Paper

Homology Modeling
Docking -molecular Interaction
Ampicillin
Lactams
Screening Generic
Monobactams
Antibiotics
Antibiotics, Antitubercular
beta-Lactams
beta-Lactamase Inhibitors

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