PMID: 11929695Apr 4, 2002Paper

A new integron carrying VIM-2 metallo-beta-lactamase gene cassette in a Serratia marcescens isolate

Diagnostic Microbiology and Infectious Disease
Jong Hwa YumYunsop Chong

Abstract

Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a bla(VIM-2) gene cassette on a class 1 integron. This finding indicates that bla(VIM-2) is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC.

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Citations

Apr 8, 2010·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Kristin HegstadSiamak P Yazdankhah
Jun 20, 2012·Antimicrobial Agents and Chemotherapy·Heime RieberYvonne Pfeifer
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Apr 1, 2011·Future Microbiology·Wei-Hua Zhao, Zhi-Qing Hu
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Apr 3, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A C Fluit, F-J Schmitz

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