PMID: 8611327Jan 1, 1996Paper

A new liposomal contrast medium for CT of the liver. An imaging study in a rabbit tumour model

Acta Radiologica
P Leander

Abstract

A new type of liposomal liver-specific contrast medium was studied in an experimental tumour model. Rabbits were inoculated with VX2-carcinoma directly in the liver of laparotomy. CT studies were carried out 14 days after inoculation. The liver-specific contrast medium consisted of a suspension of liposomes in a 100 mg I/ml iodixanol solution, with equal amounts of encapsulated and nonencapsulated iodixanol. It was administered at a dose of 200 mg I/kg. The contrast of normal liver tissue to tumorous tissue was significantly increased by contrast medium administration, the increase being largest 10 min after injection.

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Citations

Sep 14, 2010·Wiley Interdisciplinary Reviews. Systems Biology and Medicine·Gurpreet Singh SandhuJeffrey L Duerk
Jan 21, 2006·AJR. American Journal of Roentgenology·Srinivasan MukundanAnanth Annapragada
Jul 13, 2007·Acta Cirúrgica Brasileira·Rogério Saad-HossneWilliam Saad Hossne
Jun 6, 2006·Acta Cirúrgica Brasileira·Rogério Saad-HossneWilliam Saad Hossne
Nov 17, 2006·Pharmaceutical Research·V P Torchilin
Feb 21, 2019·Microscopy Research and Technique·Mümin Mehmet KoçAsa H Barber

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