Mar 1, 1976

A new look at the measurement and interpretation of enzyme assays

Annals of Clinical Biochemistry
G Ceriotti

Abstract

Some methodological problems in clinical enzymology, including instability of enzymes in the incubation mixture and requirements for optimal reaction conditions, are highlighted. The importance of a knowledge of fundamental enzyme biochemistry and physiology as the basis for their diagnostic application is stressed, and the different behaviour of some hepatic enzymes--namely, GOT, GPT, gamma-GT, and OCT, in various pathological conditions is traced back to their characteristic biochemical and physiological properties. In the field of urinary enzymes a knowledge of the ideal requirements for the enzyme investigation of the various renal functions and of the properties of potentially valuable enzymes permits a critical selection of the really useful ones.

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Mentioned in this Paper

Enzymes, antithrombotic
Gamma-glutamyl transferase
Enzymatic Biochemistry
Hepatic
Myocardium
Kidney
Enzymes for Treatment of Wounds and Ulcers
Muscle
Pathology
SGOT - Glutamate oxaloacetate transaminase

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