A new look for the growing microtubule end?

The Journal of Cell Biology
Luke M Rice

Abstract

What does the end of a growing microtubule look like? In this issue, McIntosh et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201802138) use electron tomography to provide state-of-the-art three-dimensional images of microtubule ends in cells and in vitro, yielding an unexpected answer to this fundamental question.

References

Nov 18, 2005·Nature·Ekaterina L GrishchukJ Richard McIntosh
Nov 13, 2015·Nature Reviews. Molecular Cell Biology·Anna Akhmanova, Michel O Steinmetz
Sep 13, 2016·Nature Cell Biology·Audrey GuesdonDenis Chrétien
Oct 11, 2017·Nature Structural & Molecular Biology·Joseph AthertonAnna Akhmanova
Apr 21, 2018·Nature Reviews. Molecular Cell Biology·Gary J Brouhard, Luke M Rice
May 26, 2018·The Journal of Cell Biology·J Richard McIntoshNikita Gudimchuk

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Citations

Mar 28, 2020·Protein Science : a Publication of the Protein Society·Saikat ChakrabortyWolfgang Baumeister
May 26, 2021·Current Biology : CB·Joseph M Cleary, William O Hancock

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Methods Mentioned

BETA
electron tomography
GTPase
light microscopy

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