A new magnetic resonance imaging scoring method for assessment of haemophilic arthropathy

Haemophilia : the Official Journal of the World Federation of Hemophilia
B LundinR Ljung

Abstract

In a European multicentre study, 39 ankles in 28 haemophilic boys were investigated by magnetic resonance imaging (MRI). A new MRI score was developed in the format A(e:s:h) for evaluating haemophilic arthropathy. This scheme provides high resolution and allows separation of different pathological components. The factor A is calculated as the sum of scores for subchondral cysts (maximum value 6), irregularity/erosion of subchondral cortex (maximum 4) and chondral destruction (maximum 6); e, s and h, respectively, represent effusion/haemarthrosis, synovial hypertrophy and haemosiderin deposition, and they are separately evaluated on a scale of 0-4. Working independently, two radiologists scored the 39 ankles twice using both this new 'European' scoring method and a previously published 'Denver' scoring scheme. Final classification was achieved by consensus. The reproducibility of the readings was assessed, and for both scoring methods the results indicated good or moderate intraobserver agreement, and good, moderate or fair interobserver agreement. These findings suggest that MRI can be useful for semiquantitative evaluation of haemophilic arthropathy, providing the examination is performed according to an appropriate protocol, ...Continue Reading

References

Jul 1, 1992·Journal of Internal Medicine·I M NilssonH Pettersson
Jan 1, 1992·AJR. American Journal of Roentgenology·G HermannI F Abdelwahab
Dec 1, 1991·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·C BauninA Robert
Sep 1, 1987·Acta Radiologica·H PetterssonK N Scott
Sep 1, 1987·Radiology·B S YulishM T Modic
Jul 1, 1981·Acta paediatrica Scandinavica·H PetterssonA Ahlberg
Sep 1, 1993·The Journal of Pediatrics·R NussM Manco-Johnson
Jun 1, 1996·Baillière's Clinical Haematology·E Berntorp
Jun 3, 1998·British Journal of Haematology·R C Ljung
Jan 5, 1999·Haemophilia : the Official Journal of the World Federation of Hemophilia·W KreuzB Kornhuber
May 3, 2000·Haemophilia : the Official Journal of the World Federation of Hemophilia·R NussM Manco-Johnson
Dec 21, 2000·Haemophilia : the Official Journal of the World Federation of Hemophilia·R NussJ Murphy
Apr 16, 2002·Haemophilia : the Official Journal of the World Federation of Hemophilia·M B FunkW Kreuz
Apr 18, 2002·European Radiology·R SolerM Marini
Feb 1, 2003·Haemophilia : the Official Journal of the World Federation of Hemophilia·M DobónA Ferrández
Mar 18, 2003·Seminars in Thrombosis and Hemostasis·Ray F Kilcoyne, Rachelle Nuss
Jan 1, 1995·Haemophilia : the Official Journal of the World Federation of Hemophilia·J M Lusher

❮ Previous
Next ❯

Citations

Jan 22, 2005·Haemophilia : the Official Journal of the World Federation of Hemophilia·B M FeldmanV S Blanchette
Mar 22, 2006·Acta Haematologica·Amy L Dunn, Thomas C Abshire
May 23, 2014·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Tuba H KarapnarHale Ören
Oct 30, 2012·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Hortensia De la Corte-Rodriguez, E Carlos Rodriguez-Merchan
Dec 18, 2013·Seminars in Ultrasound, CT, and MR·Susan CrossNicos Fotiadis
Sep 25, 2015·Indian Journal of Pediatrics·Arun Kumar Gupta, Manisha Jana
Jun 3, 2015·Haemophilia : the Official Journal of the World Federation of Hemophilia·H M van den BergA Srivastava
Oct 14, 2004·Haemophilia : the Official Journal of the World Federation of Hemophilia·M J Manco-JohnsonV S Blanchette
Apr 7, 2005·Haemophilia : the Official Journal of the World Federation of Hemophilia·B LundinUNKNOWN International Prophylaxis Study Group
Apr 7, 2005·Haemophilia : the Official Journal of the World Federation of Hemophilia·H ChambostUNKNOWN Pednet Group
Apr 7, 2005·Haemophilia : the Official Journal of the World Federation of Hemophilia·B LundinUNKNOWN European Paediatric Network for Haemophilia Management (PEDNET)
Feb 16, 2006·Haemophilia : the Official Journal of the World Federation of Hemophilia·S Donadel-Claeyssens, UNKNOWN European Paediatric Network for Haemophilia Management
Mar 8, 2007·British Journal of Haematology·Leslie Raffini, Catherine Manno
May 11, 2006·Haemophilia : the Official Journal of the World Federation of Hemophilia·K BeetonR Vachalathiti
Apr 29, 2006·Haemophilia : the Official Journal of the World Federation of Hemophilia·H PergantouS Aronis
Jun 25, 2008·Haemophilia : the Official Journal of the World Federation of Hemophilia·B M FeldmanUNKNOWN International Prophylaxis Study Group (IPSG)
Oct 18, 2007·Haemophilia : the Official Journal of the World Federation of Hemophilia·N J Goddard, H Mann
Aug 22, 2006·Haemophilia : the Official Journal of the World Federation of Hemophilia·A S DoriaUNKNOWN Expert MRI Working Group of the International Prophylaxis Study Group
Jan 9, 2008·Haemophilia : the Official Journal of the World Federation of Hemophilia·A S DoriaUNKNOWN Expert Imaging Working Group of The International Prophylaxis Study Group
Jan 11, 2007·Haemophilia : the Official Journal of the World Federation of Hemophilia·S Schulman, A Eelde
May 15, 2007·Haemophilia : the Official Journal of the World Federation of Hemophilia·K ZukotynskiA S Doria
Jul 7, 2012·Haemophilia : the Official Journal of the World Federation of Hemophilia·B LundinUNKNOWN International Prophylaxis Study Group
Mar 26, 2011·Haemophilia : the Official Journal of the World Federation of Hemophilia·I E M Den UijlK Fischer
Aug 8, 2013·Haemophilia : the Official Journal of the World Federation of Hemophilia·M W ChanA S Doria
Oct 18, 2011·Haemophilia : the Official Journal of the World Federation of Hemophilia·M Muça-PerjaA Gringeri
Jun 29, 2012·Haemophilia : the Official Journal of the World Federation of Hemophilia·P PoonnooseB M Feldman
Nov 13, 2010·Haemophilia : the Official Journal of the World Federation of Hemophilia·D MelchiorreM Morfini
Sep 10, 2010·Haemophilia : the Official Journal of the World Federation of Hemophilia·H TakedaniT Fujii
Sep 21, 2011·Haemophilia : the Official Journal of the World Federation of Hemophilia·E C Rodriguez-MerchanA Caffarini
Sep 6, 2012·Haemophilia : the Official Journal of the World Federation of Hemophilia·Paul E MonahanVictor Jiménez-Yuste
Jun 25, 2014·European Journal of Haematology. Supplementum·Françoise BoehlenErik Berntorp
Jan 1, 2014·Haemophilia : the Official Journal of the World Federation of Hemophilia·W FoppenK Fischer
Jul 16, 2010·Haemophilia : the Official Journal of the World Federation of Hemophilia·A S Doria
Apr 26, 2014·Haemophilia : the Official Journal of the World Federation of Hemophilia·V S BlanchetteJ N Mahlangu
Jan 7, 2015·European Journal of Haematology·Rudolf SchwarzUlf Tedgård
Dec 4, 2014·Haemophilia : the Official Journal of the World Federation of Hemophilia·J OldenburgUNKNOWN Cross-sectional MRI study investigators
Oct 12, 2013·Haemophilia : the Official Journal of the World Federation of Hemophilia·C Sierra AisaD Rubio Félix
Oct 14, 2009·Clinical Radiology·A JelbertN Fotiadis
Jan 24, 2006·Seminars in Hematology·Pradeep M Poonnoose, Alok Srivastava
Sep 25, 2009·Blood Reviews·Rolf Ljung
Sep 17, 2016·Haemophilia : the Official Journal of the World Federation of Hemophilia·K FischerUNKNOWN participants of the International Symposium on Outcome Measures in Hemophilic Arthropathy
Mar 24, 2017·European Journal of Haematology·Cedric HermansSilva Zupančić Šalek
Jun 3, 2017·Haemophilia : the Official Journal of the World Federation of Hemophilia·M SolimanA S Doria
Jan 25, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Annette von DrygalskiEric Y Chang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Haemophilia : the Official Journal of the World Federation of Hemophilia
B LundinInternational Prophylaxis Study Group
Haemophilia : the Official Journal of the World Federation of Hemophilia
M DobónA Ferrández
Haemophilia : the Official Journal of the World Federation of Hemophilia
R NussM J Manco-Johnson
Haemophilia : the Official Journal of the World Federation of Hemophilia
R Kilcoyne, R Nuss
© 2022 Meta ULC. All rights reserved