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A new mechanism of tumor resistance to the immune system, based on tryptophan breakdown by indoleamine 2,3-dioxygenase

Bulletin et mémoires de l'Académie royale de médecine de Belgique

May 11, 2004

B Van den Eynde

PMID: 15132006

Abstract

T lymphocytes represent the main effectors of the immune response that can lead to tumor rejection, which represents the aim of various approaches of immunotherapy that are currently tested. However, in many cases, tumor cells appear to resist immune rejection. We have recently uncovere...read more

Mentioned in this Paper

Tryptophan Catabolic Process
Tumor Cells, Uncertain Whether Benign or Malignant
Immune Response
Immune System
Tryptophan
Immune Resistance
T-Lymphocyte
Tumor Escape
Neoplasms
Sustain
Paper Details
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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

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Catherine UyttenhoveBenoît J Van den Eynde
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A new mechanism of tumor resistance to the immune system, based on tryptophan breakdown by indoleamine 2,3-dioxygenase

Bulletin et mémoires de l'Académie royale de médecine de Belgique

May 11, 2004

B Van den Eynde

PMID: 15132006

DOI:

Abstract

T lymphocytes represent the main effectors of the immune response that can lead to tumor rejection, which represents the aim of various approaches of immunotherapy that are currently tested. However, in many cases, tumor cells appear to resist immune rejection. We have recently uncovere...read more

Mentioned in this Paper

Tryptophan Catabolic Process
Tumor Cells, Uncertain Whether Benign or Malignant
Immune Response
Immune System
Tryptophan
Immune Resistance
T-Lymphocyte
Tumor Escape
Neoplasms
Sustain

Similar Papers Found In These Feeds

The Nuffield Department of Medicine

Find the latest research from the Nuffield Department of Medicine at the University of Oxford here.

Immune System in Humans: Tissues & Ages

Mapping the human immune system spatially, within and between tissues, will provide the basis for studying mechanisms of tissue residency and the effects of aging. Find new research on analysis of the immune system by multiple approaches here.

Related Papers

Nature Medicine

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Nature MedicineSeptember 23, 2003
Catherine UyttenhoveBenoît J Van den Eynde
Paper Details
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    References currently unavailable

    We're still populating references for this paper, please check back later.
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