A new method for detecting causality in fMRI data of cognitive processing.

Cognitive Processing
Alessandro LondeiMarta Olivetti Belardinelli

Abstract

One of the most important achievements in understanding the brain is that the emergence of complex behavior is guided by the activity of brain networks. To fully apply this theoretical approach fully, a method is needed to extract both the location and time course of the activities from the currently employed techniques. The spatial resolution of fMRI received great attention, and various non-conventional methods of analysis have previously been proposed for the above-named purpose. Here, we briefly outline a new approach to data analysis, in order to extract both spatial and temporal activities from fMRI recordings, as well as the pattern of causality between areas. This paper presents a completely data-driven analysis method that applies both independent components analysis (ICA) and the Granger causality test (GCT), performed in two separate steps. First, ICA is used to extract the independent functional activities. Subsequently the GCT is applied to the independent component (IC) most correlated with the stimuli, to indicate its causal relation with other ICs. We therefore propose this method as a promising data-driven tool for the detection of cognitive causal relationships in neuroimaging data.

References

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Citations

Jun 27, 2014·PloS One·Fa-Hsuan LinJohn W Belliveau
Apr 22, 2006·Cognitive Processing·P BelardinelliG L Romani
Jan 31, 2012·Neuroscience Research·Jong-Hwan LeeSeung-Schik Yoo
Jul 2, 2011·Neural Networks : the Official Journal of the International Neural Network Society·Yasuhiro SogawaSeiya Imoto
May 7, 2010·Magnetic Resonance Imaging·Baxter P RogersJohn C Gore
Apr 25, 2007·Brain Research Bulletin·A LondeiM Olivetti Belardinelli
Apr 21, 2009·Human Brain Mapping·Fa-Hsuan LinMatti S Hämäläinen
Jan 28, 2009·Human Brain Mapping·Michael C StevensVince D Calhoun
Nov 9, 2007·Human Brain Mapping·Vincent van de VenFabrizio Esposito
Nov 30, 2012·Journal of the Royal Statistical Society. Series A, (Statistics in Society)·Odd O AalenBruno Ledergerber
Sep 26, 2009·Human Brain Mapping·Alessandro LondeiMarta Olivetti Belardinelli
Aug 25, 2009·NeuroImage·Vasily A VakorinAnthony R McIntosh
Nov 7, 2020·Computers in Biology and Medicine·Rik J C van EschPaul M J Van den Hof

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