PMID: 11924730Apr 2, 2002Paper

A new method for evaluation of split renal cortical blood flow with contrast echography

Hypertension Research : Official Journal of the Japanese Society of Hypertension
Yoko HosotaniMasakazu Kohno

Abstract

The recent development of contrast echography has made renal enhancement possible through an intravenous injection of microbubble-based contrast. In animal models, tissue perfusion can be quantified using contrast echography by measurement of the rate at which microbubbles replenish tissue after their ultrasound-induced destruction. Our purpose in this study was to evaluate renal blood flow with contrast echography in humans. To increase the sensitivity for microbubbles, we used a combination of power Doppler harmonic and intermittent imaging. The pulsing interval (PI) was changed from 10 cardiac cycles to 1 cardiac cycle during an intravenous infusion of the contrast agent, and alterations in the intensity of the renal cortex were represented as a decline ratio (DR). In 24 patients with various renal diseases, we were able to observe all 48 kidneys with adequate enhancement of the renal cortex. At PI of 10 cardiac cycles, the enhancement was homogeneous and strong, while, obviously, changing PI from 10 to 1 cardiac cycles caused a decline of enhancement. An excellent correlation was found between DR using contrast echography and renal plasma flow determined by clearance and radionuclide measurements. An excellent correlation w...Continue Reading

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Citations

Jul 25, 2009·American Journal of Physiology. Renal Physiology·Kambiz KalantariniaKevin Wei
Jun 19, 2010·International Heart Journal·Kayori TsuruokaFumio Tsujimoto
Jun 22, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Antoine G SchneiderBruno Vogt
Apr 26, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Fang MaAi Peng
Dec 1, 2008·Journal of Medical Ultrasonics·Satoshi OkayamaYoshihiko Saito
Feb 15, 2011·International Journal of Nephrology·Sajid Melvin George, Kambiz Kalantarinia
Jan 1, 2007·Drug Discovery Today. Disease Mechanisms·Kambiz Kalantarinia, Mark D Okusa
Apr 7, 2005·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mahesh S Mulumudi, Christopher J White
Jun 17, 2004·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Noriko KishimotoToshiji Iwasaka
Nov 28, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Michinobu NagaoJunpei Ikezoe
Oct 3, 2003·Radiologic Clinics of North America·Michelle L RobbinRichard G Barr
Feb 16, 2018·The Veterinary Record·Emmelie StockKatrien Vanderperren
Jul 18, 2019·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Marcel H A MuskietDaniël H van Raalte
Nov 25, 2017·Journal of Veterinary Internal Medicine·E StockK Vanderperren
Jun 17, 2018·Critical Care : the Official Journal of the Critical Care Forum·Anatole HarroisJacques Duranteau
Oct 12, 2021·Experimental and Therapeutic Medicine·Chen-Chen HangShuo Wang

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