PMID: 9434940Jan 22, 1998Paper

A new mutation Rim3 resembling Re(den) is mapped close to retinoic acid receptor alpha (Rara) gene on mouse chromosome 11

Mammalian Genome : Official Journal of the International Mammalian Genome Society
H SatoM Tama

Abstract

A new mouse mutation, recombination-induced mutation 3 (Rim3), arose spontaneously in our mouse facility. This mutation exhibits corneal opacity as well as abnormal skin and hair development resembling rex denuded (Re(den)) and bareskin (Bsk). Large-scale linkage analysis with two kinds of intersubspecific backcrosses revealed that Rim3 is mapped to the distal portion of Chromosome (Chr) 11, in which Re(den) and Bsk have been located, and is very close to the retinoic acid receptor, alpha (Rara). The genes, keratin gene complex-1, acidic, gene 10, 12 (Krt1-10, 12), granulin (Grn), junctional plakoglobin (Jup) and Rara, all of which regulate growth and differentiation of epithelial cells, are genetically excluded as candidate genes for Rim3, but are clustered in the short segment on mouse Chr 11.

References

Jan 1, 1992·Mammalian Genome : Official Journal of the International Mammalian Genome Society·J H NadeauS Varmuza
Oct 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·M ShoyabG D Plowman
Jan 1, 1988·Annual Review of Biochemistry·P M Steinert, D R Roop
Nov 1, 1993·Current Eye Research·C Y LiuW W Kao
Jun 1, 1994·Current Opinion in Genetics & Development·E B Lane
Mar 1, 1995·Nature Genetics·W H McLeanC Higgins
May 1, 1995·Mammalian Genome : Official Journal of the International Mammalian Genome Society·J L GuénetR Kemler
Jan 1, 1993·Mammalian Genome : Official Journal of the International Mammalian Genome Society·J T Eppig, L J Maltais
Jan 1, 1993·Mammalian Genome : Official Journal of the International Mammalian Genome Society·K F Manly
Jan 1, 1994·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·T SudaR Kominami
Sep 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·M BucanG L Gerton

❮ Previous
Next ❯

Citations

Apr 23, 2010·Genes & Genetic Systems·Hiromitsu KomiyamaToshihiko Shiroishi
Mar 29, 2014·PloS One·Marta Hergueta-RedondoGema Moreno-Bueno
Aug 12, 2008·Genesis : the Journal of Genetics and Development·Tomoaki FujiiToshihiko Shiroishi
Jun 19, 2007·Biochemical and Biophysical Research Communications·Shigekazu TanakaToshihiko Shiroishi
Mar 2, 2005·The Journal of Investigative Dermatology·Declan P LunnyRebecca M Porter
Apr 1, 2015·The Biochemical Journal·Peiliang ShiXiang Gao
Dec 14, 2011·The American Journal of Pathology·Yue ZhouXiang Gao
Jul 28, 2016·Cellular and Molecular Life Sciences : CMLS·Carmen Ehrmann, Marlon R Schneider
Nov 7, 2019·Nature Reviews. Immunology·Petr BrozFeng Shao
Apr 3, 2020·Journal of Cell Communication and Signaling·Danbin WuMaojuan Guo
Apr 16, 2020·Acta Biochimica Et Biophysica Sinica·Zengzhang ZhengXing Liu
Jul 15, 2015·The Biochemical Journal·Masaru Tamura, Toshihiko Shiroishi
Apr 5, 2000·The Journal of Biological Chemistry·A MäättäF M Watt
Mar 12, 2021·Nature Reviews. Drug Discovery·Xing LiuJudy Lieberman
Mar 24, 1999·Genomics·H SatoT Shiroishi
Jul 13, 2021·Developmental and Comparative Immunology·Hao ChenDahai Yang
Sep 20, 2021·Journal of Molecular Biology·Sebastian Rühl, Petr Broz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.