A new phylogenetic group of Propionibacterium acnes

Journal of Medical Microbiology
Andrew McDowellSheila Patrick

Abstract

Immunofluorescence microscopy-based identification of presumptive Propionibacterium acnes isolates, using the P. acnes-specific mAb QUBPa3, revealed five organisms with an atypical cellular morphology. Unlike the coryneform morphology seen with P. acnes types I and II, these isolates exhibited long slender filaments (which formed large tangled aggregates) not previously described in P. acnes. No reaction with mAbs that label P. acnes types IA (QUBPa1) and II (QUBPa2) was observed. Nucleotide sequencing of the 16S rRNA gene (1484 bp) revealed the isolates to have between 99.8 and 99.9 % identity to the 16S rRNA gene of the P. acnes type IA, IB and II strains NCTC 737, KPA171202 and NCTC 10390, respectively. Analysis of the recA housekeeping gene (1047 bp) did reveal, however, a greater number of conserved nucleotide polymorphisms between the sequences from these isolates and those from NCTC 737 (98.9 % identity), KPA171202 (98.9 % identity) and NCTC 10390 (99.1 % identity). Phylogenetic investigations demonstrated that the isolates belong to a novel recA cluster or lineage distinct from P. acnes types I and II. We now propose this new grouping as P. acnes type III. The prevalence and clinical importance of this novel recA lineag...Continue Reading

References

Oct 1, 1979·Applied and Environmental Microbiology·M KishishitaY Ito
Jan 1, 1978·Applied and Environmental Microbiology·K J McGinleyJ J Leyden
Jan 1, 1978·Journal of Clinical Microbiology·G F Webster, C S Cummins
Sep 1, 1991·Reviews of Infectious Diseases·I Brook, E H Frazier
Aug 1, 1994·The Journal of Applied Bacteriology·J M Young, C M Triggs
Dec 1, 1996·Plastic and Reconstructive Surgery·C Y AhnW W Shaw
Oct 23, 1997·International Journal of Systematic Bacteriology·T PalysF M Cohan
Feb 19, 1998·Oral Microbiology and Immunology·A Le GoffM Bonnaure-Mallet
Jul 27, 2002·Annual Review of Microbiology·Frederick M Cohan
Nov 13, 2003·FEMS Microbiology Letters·Alexandra L PerryTom S J Elliott
Aug 3, 2004·Science·Holger BrüggemannGerhard Gottschalk
Jan 7, 2005·Journal of Clinical Microbiology·Andrew McDowellSheila Patrick

❮ Previous
Next ❯

Citations

Jun 28, 2011·Journal of Bacteriology·Judit HunyadkürtiIstván Nagy
Mar 1, 2012·Journal of Bacteriology·Andrea VörösIstván Nagy
Jan 20, 2012·Journal of Clinical Microbiology·Mogens KilianHans B Lomholt
Aug 31, 2010·BMC Microbiology·Carsten HollandHolger Brüggemann
Dec 7, 2013·BioMed Research International·María Eugenia PortilloAndrej Trampuz
Jan 24, 2014·BioMed Research International·Andrew McDowellAnne Eady
Feb 21, 2014·Molecular Biology and Evolution·Andrea CampisanoOmar Rota-Stabelli
Jan 29, 2016·International Orthopaedics·Zhe ChenYuehuan Zheng
Aug 11, 2012·Anaerobe·O A Alexeyev, A C Jahns
Feb 19, 2011·International Journal of Food Microbiology·Susana DelgadoBaltasar Mayo
Jun 10, 2009·Diagnostic Microbiology and Infectious Disease·Marta Fernandez SampedroRobin Patel
Oct 8, 2009·The Journal of Investigative Dermatology·Christos C Zouboulis
Feb 24, 2012·The British Journal of Dermatology·A C JahnsO A Alexeyev
Oct 19, 2011·International Journal of Dermatology·Silvana Maria de Morais CavalcantiVera Magalhães
Jan 21, 2015·The British Journal of Dermatology·Y YuJ Kim
May 13, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Yolande HauckChristine Pourcel
Nov 27, 2015·The Indian Journal of Medical Research·Murali SowmiyaHajib N Madhavan
Aug 30, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S Romano-BertrandE Jumas-Bilak
Jul 16, 2016·International Journal of Dermatology·Hyuck Hoon Kwon, Dae Hun Suh
Apr 22, 2016·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Stefan DudliJeffrey C Lotz
Jun 5, 2016·International Journal of Systematic and Evolutionary Microbiology·Guillaume Ghislain AubinStephane Corvec
Mar 19, 2016·The Journal of Physiology·Emma Barnard, Huiying Li
Apr 8, 2016·The Journal of Bone and Joint Surgery. American Volume·Jason E HsuFrederick A Matsen
Mar 17, 2009·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Jeremiah A LyonsShelley J Newman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.