A new platelet function test

Thrombosis Research
W L RyanE Sullivan

Abstract

A method for screening EDTA(K3) blood samples for platelet function is described. The general availability of whole blood platelet counters in the clinical laboratory suggested their use to measure platelet aggregation. To simplify the collection and storage of blood samples, a method utilizing EDTA collected blood is described. Addition of calcium and citrate restores platelet function to blood samples even when stored at room temperature for several hours. Thus, the blood sample used to assay RBC, WBC and platelet parameters may also be employed in platelet aggregation. A comparison of this method with aggregometry on 120 subjects indicated a similar response to arachidonate, collagen, ristocetin and ADP.

References

Jul 1, 1986·Journal of Clinical Pathology·D A YardumianS J Machin
Jun 19, 1986·Biochimica Et Biophysica Acta·J A Malinski, G L Nelsestuen
Jun 1, 1986·Thrombosis Research·R Setiabudy-Dharma, Y Funahara
Jul 27, 1972·The New England Journal of Medicine·L A Harker, S J Slichter
Jun 1, 1984·British Journal of Clinical Pharmacology·W MeisterP C Weber
May 15, 1981·Thrombosis Research·M J Mant, L A Bach
Feb 1, 1980·Journal of Pharmacological Methods·D C Cardinal, R J Flower

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Citations

Apr 11, 2015·Lupus Science & Medicine·Anum FayyazR Hal Scofield
Jul 10, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Michael T BrennanCraig S Miller
Jul 25, 2008·Journal of Dental Research·M T BrennanP B Lockhart
Jul 18, 2012·The Journal of Craniofacial Surgery·Yunqiang YangYan Wang

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