PMID: 7521648Oct 1, 1994Paper

A new process for the production of clinical dextran by mixed-culture fermentation of Lipomyces starkeyi and Leuconostoc mesenteroides

Enzyme and Microbial Technology
D Kim, D F Day

Abstract

A mixed-culture fermentation system was designed for the production of size-limited dextrans. This process was simpler and more economical than traditional methods. It required the establishment of microbial consortia of Lipomyces starkeyi ATCC 74054 and Leuconostoc mesenteroides ATCC 10830. Controlling initial conditions, growth, and enzyme production by both organisms controlled the product size. In this process, both strains were grown separately and then mixed. Dextran fermentation was then allowed to proceed. At the desired time (and molecular size), the fermentation was harvested. The optimum pH and temperature for production of clinical dextran (75,000 MW) were 5.2 (+/- 0.1) and 28 (+/- 0.5) degrees C, respectively. Varying the ratio of L. mesenteroides to L. starkeyi in the inoculum did not significantly affect either the final cell ratios or dextran production.

References

Jul 1, 1979·Biotechnology and Bioengineering·G R LawfordH G Lawford
Jan 16, 1992·Biochimica Et Biophysica Acta·E MbembaL Gattegno
Feb 1, 1986·Archives of Disease in Childhood·H HurvitzD Branski
Jul 15, 1961·Nature·R W BAILEY, E J BOURNE
Apr 1, 1952·The Biochemical Journal·C R RICKETTS

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Citations

Jun 10, 2005·Microbiology and Molecular Biology Reviews : MMBR·Elvira KhalikovaTimo Korpela
Jan 15, 2010·Journal of Applied Microbiology·J BaderU Stahl
Apr 18, 2015·International Journal of Biological Macromolecules·Rashida Rahmat ZohraShah Ali Ul Qader
Feb 13, 2013·Carbohydrate Polymers·Rashida Rahmat ZohraShah Ali Ul Qader
Jul 26, 2016·Frontiers in Microbiology·Florian OswaldChristoph Syldatk
Sep 14, 2018·World Journal of Microbiology & Biotechnology·Bonnie A McNeil, David T Stuart
Oct 23, 2019·Marine Drugs·Xiaohua LaiAnd Shujun Wang
Dec 26, 2016·Journal of Industrial Microbiology & Biotechnology·Yu-Qi ZhangXue-Qin Hu
Mar 6, 2021·Microbial Cell Factories·Zi-Xu LiuJu-Zheng Sheng
Jul 23, 2020·Biotechnology Reports·Varucha MisraMohammad Israil Ansari

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