A new strategy for craniospinal axis localization and adaptive dosimetric evaluation using cone beam CT.

Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology
K Mohamathu RaficPaul B Ravindran

Abstract

Computational complexities encountered in craniospinal irradiation (CSI) have been widely investigated with different planning strategies. However, localization of the entire craniospinal axis (CSA) and evaluation of adaptive treatment plans have traditionally been ignored in CSI treatment. In this study, a new strategy for CSI with comprehensive CSA localization and adaptive plan evaluation has been demonstrated using cone beam CT with extended longitudinal field-of-view (CBCTeLFOV). Multi-scan CBCT images were acquired with fixed longitudinal table translations (with 1 cm cone-beam overlap) and then fused into a single DICOM-set using the custom software coded in MatLab™. A novel approach for validation of CBCTeLFOV was demonstrated by combined geometry of Catphan-504 and Catphan-604 phantoms. To simulate actual treatment scenarios, at first, the end-to-end workflow of CSI with VMAT was investigated using an anthropomorphic phantom and then applied for two patients (based on random selection). The fused CBCTeLFOV images were in excellent agreement with planning CT (pCT). The custom developed software effectively manages spatial misalignments arising out of the uncertainties in treatment/setup geometry. Although the structures...Continue Reading

References

Jan 18, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C Clifton LingZvi Fuks
May 1, 2007·International Journal of Radiation Oncology, Biology, Physics·Atmaram Pai PanandikerDeborah Citrin
Apr 14, 2009·International Journal of Radiation Oncology, Biology, Physics·Wilko F A R VerbakelSuresh Senan
Nov 26, 2009·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Yi RongBhudatt Paliwal
Jun 22, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jan SeppäläHeikki Minn
Feb 25, 2011·International Journal of Radiation Oncology, Biology, Physics·Young K LeeFrank H Saran
Mar 23, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Antonella FogliataDamien C Weber
May 19, 2011·Journal of Applied Clinical Medical Physics·Ryan L McMahonQ Jackie Wu
Mar 23, 2012·International Journal of Radiation Oncology, Biology, Physics·Fred CaoAnand Karvat
Dec 20, 2012·Current Cancer Therapy Reviews·Ticiana LealH Ian Robins
Jun 25, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Pamela MyersNiko Papanikolaou
Jun 11, 2014·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Austin Hadley, George X Ding
Apr 11, 2015·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Anna Bandurska-LuqueJoanna Kaźmierska
Dec 25, 2015·Journal of Applied Clinical Medical Physics·Young K LeeAliaksandr Karotki
Sep 8, 2016·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Andrej StrojnikPrimož Peterlin
Mar 21, 2018·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·K Mohamathu RaficB Paul Ravindran
May 8, 2018·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Keqiang WangYuanming Feng
Jun 4, 2019·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·K Mohamathu RaficB Paul Ravindran

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