A new treatment of alopecia induced by palbociclib: Topical cetirizine.

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
Gemma CaroAlfredo Rossi

Abstract

Recently CDK4/6 inhibitors have been introduced for the treatment of hormone positive breast cancer resistant to endocrine therapy. Among their side effects, alopecia is often reported being associated to patients' distress and depressive symptoms. We report the case of a 70-year-old woman affected by breast cancer in treatment with Palbociclib, who developed alopecia.Management and Outcome: We prescribed a topical solution with cetirizine. Global photography, trichoscopy and trichogram were assessed. All evaluations demonstrated alopecia improvement. Currently, no treatment options for CDK 4/6 inhibitors induced alopecia have been proposed. Herein, we report the use of topical cetirizine.

References

Nov 8, 2013·Breast Cancer Research and Treatment·Lisa GallicchioKathy J Helzlsouer
Jun 2, 2015·The New England Journal of Medicine·Nicholas C TurnerUNKNOWN PALOMA3 Study Group
Jun 13, 2017·The Journal of Dermatological Treatment·A RossiM Carlesimo
Jul 12, 2018·Journal of Cosmetic Dermatology·Alfredo RossiMarta Carlesimo

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Checkpoints & Regulators

Cell cycle checkpoints are a series of complex checkpoint mechanisms that detect DNA abnormalities and ensure that DNA replication and repair are complete before cell division. They are primarily regulated by cyclins, cyclin-dependent kinases, and the anaphase-promoting complex/cyclosome. Here is the latest research.

Related Papers

Clinica nuova; rassegna del progresso medico internazionale
Postgraduate Medical Journal
K Sibley
Vestnik dermatologii i venerologii
E A Ludianskiĭ
© 2022 Meta ULC. All rights reserved