PMID: 6130453Dec 6, 1982

A new type of enzyme electrode: the ascorbic acid eliminator electrode

Life Sciences
Géza NagyR N Adams

Abstract

A new type of enzyme electrode has been developed for in vivo electrochemical measurements which allows discrimination between ascorbic acid and catecholamines and their metabolites. The electrode employs the enzyme ascorbic acid oxidase held between the voltammetric electrode and solution by a dialysis membrane or immobilized on the outer surface of serous membrane from rat small intestine. The electrode gives linear calibration curves for all catecholamines and metabolites independent of any ascorbic acid concentrations significant in physiological measurements. The electrode has been tested in brain slice measurements and shown to respond to releases of catecholamines initiated by potassium ion stimulation.

References

Jun 3, 1967·Nature·S J Updike, G P Hicks

Citations

Jul 30, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·J Racek, J Musil
Oct 1, 1985·Brain Research·J A Stamford
Mar 1, 1984·Journal of Neuroscience Methods·P M KovachR M Wightman
Jul 1, 1986·Journal of Neuroscience Methods·J A Stamford
Oct 1, 1989·Trends in Neurosciences·J A Stamford
Jun 1, 1983·Brain Research Bulletin·C D Blaha, R F Lane
Jan 1, 1991·Biosensors & Bioelectronics·E N NaveraI Karube
Jun 26, 2008·Chemical Reviews·Donita L RobinsonR M Wightman
May 24, 2006·Journal of Biochemical and Biophysical Methods·Livia NagyGéza Nagy
Jan 9, 1984·Brain Research·G A GerhardtR N Adams
Aug 1, 1988·Analytical Chemistry·J Wang, M S Lin
Oct 17, 2007·The FEBS Journal·G S Wilson, Malika Ammam
Sep 17, 2013·Angewandte Chemie·Aysu Yarman, Frieder W Scheller
Dec 26, 2001·Chemical Reviews·G S Wilson, Y Hu

Related Concepts

Metazoa
Brain Chemistry
Catecholamines
Electrochemistry
Electrode
Ovoperoxidase
August Rats
Neurosteroids
Rats, Laboratory
Ascorbate Peroxidases

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