A novel antimicrobial agent from the leaves of Peltophorum vogelianum (Benth.)

Natural Product Research
M ParveenMohammed Ali

Abstract

The methanolic extract of the leaves of Peltophorum vogelianum (Caesalpiniaceae) afforded a new phytoconstituent, 2-methoxy-4,5-dihydroxy-1(7,8-dihydroxyethylene)-8-beta-D-glucuropyranoside named as peltophorumyl-beta-D-glucuropyranoside (5), along with four known phytoconstituents, 1-pentatriacontanol (1), friedelin (2), beta-sitosterol (3) and beta-sitosterol-beta-D-glucopyranoside (4), which have not been isolated previously from this plant. Their structures were established on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT, HSQC, HMBC and MS). Moreover, compound 5 showed significant antimicrobial activity.

References

Feb 14, 1998·Journal of Natural Products·H ChávezA G González
Dec 15, 2004·Archives of Pharmacal Research·Phan Van KiemYoung Ho Kim
Jan 14, 2005·Archives of Pharmacal Research· Azhar-ul-HaqPir Muhammad
Mar 31, 2007·Natural Product Research·Rivaldo NieroFranco Delle Monache
Dec 7, 2007·Phytochemistry·Laxminarain MisraRakesh Tuli

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Citations

Oct 13, 2011·Natural Product Research·Ofentse MazimbaRunner R T Majinda
Jun 20, 2012·Natural Product Research·H HuangM Xia
Sep 1, 2018·Applied Biochemistry and Biotechnology·Habib MosbahBoulbaba Selmi

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Methods Mentioned

BETA
column chromatography
NMR

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