A novel approach for enhanced nanoparticle-sized bone substitute adhesion to chemically treated peri-implantitis-affected implant surfaces: an in vitro proof-of-principle study

Journal of Periodontology
Ahmed Yousef GamalVincent J Iacono

Abstract

The objective of this study is to evaluate micro and nano-hydroxyapatite (NHA) blended clot adhesion to citric acid-conditioned peri-implantitis-affected surfaces. Forty hopeless implants with peri-implantitis designated for removal were included in this study. Implants were divided into eight groups of five each: group 1 (G1) test areas were coated with hydroxyapatite of a microparticle size (MHA); group 2 (G2) test areas were coated with NHA; group 3 (G3) implants were coated with MHA after surface conditioning using citric acid; group 4 (G4) samples were treated in the same manner as in G3 except for the use of NHA; group 5 (G5) samples were coated without surface treatment with MHA mixed with whole human blood; group 6 (G6) implant samples were treated in the same manner as in G5 except for the use of NHA; group 7 (G7) implant samples were treated in the same way as in G5 plus surface conditioning using citric acid; and group 8 (G8) samples were treated in the same manner as in G7 except for the use of NHA. All implants in all groups were agitated for 3 minutes in phosphate-buffered saline. All samples were prepared for scanning electron microscopy evaluation. G1 and G2 non-etched implants coated with MHA or NHA sizes were ...Continue Reading

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Citations

Jan 1, 2014·Advances in Medicine·Eli E Machtei
Feb 5, 2021·Journal of Periodontal Research·Jairo M CordeiroValentim A R Barão

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