A novel approach to the CDE ring system of pectenotoxin-4 triggered by VO(acac)(2)-induced epoxy-acetalization

Organic Letters
Sarah Carley, Margaret A Brimble

Abstract

A novel approach to the CDE fragment of pectenotoxin-4 is described wherein the bicyclic acetal is constructed via a cascade cyclization induced by VO(acac)(2) epoxidation of a homoallylic alcohol.

References

Oct 3, 1999·Microscopy Research and Technique·I SpectorM R Bubb
Nov 30, 2002·Angewandte Chemie·David A EvansDirk Stenkamp
Aug 18, 2004·Accounts of Chemical Research·Yian Shi
Oct 8, 2004·Organic Letters·Petri M Pihko, Jatta E Aho
Jun 17, 2005·Organic Letters·Rosliana HalimJörn Merten
Jul 11, 2006·Toxicon : Official Journal of the International Society on Toxinology·Christopher Owen MilesPatrick T Holland
Feb 9, 2007·Organic Letters·Danielle Vellucci, Scott D Rychnovsky
Feb 9, 2007·Organic Letters·Stephen D LotestaLawrence J Williams
Jun 30, 2007·Journal of Molecular Biology·John S AllinghamIvan Rayment

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Citations

Nov 1, 2012·Chemical Reviews·Zhi-Liang ShenTeck-Peng Loh
Apr 12, 2011·Organic Letters·Daniel P Canterbury, Glenn C Micalizio
Oct 30, 2012·Organic Letters·Ozora KuboGlenn C Micalizio
Feb 4, 2010·Organic Letters·Sipak JoyasawalLawrence J Williams
Dec 5, 2012·Organic & Biomolecular Chemistry·Antonia KouridakiGeorgios Vassilikogiannakis
Nov 30, 2013·Angewandte Chemie·Kenshu FujiwaraTakanori Suzuki
Jun 29, 2010·The Journal of Organic Chemistry·Yan Zou, Alexander Deiters
Feb 9, 2012·The Journal of Organic Chemistry·Ulf Scheffler, Rainer Mahrwald
Apr 16, 2013·The Journal of Organic Chemistry·Tyler T AdintClark R Landis
Apr 21, 2012·Organic Letters·Antonia KouridakiGeorgios Vassilikogiannakis
Mar 5, 2013·Organic Letters·Ian Paterson, Gregory W Haslett

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