A novel assessment of local impedance during catheter ablation: initial experience in humans comparing local and generator measurements

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Melanie GunawardeneChristian Meyer

Abstract

A novel measure of local impedance (LI) has been found to predict lesion formation during radiofrequency current (RFC) catheter ablation. The aim of this study was to investigate the utility of this novel approach, while comparing LI to the well-established generator impedance (GI). In 25 consecutive patients with a history of atrial fibrillation, catheter ablation was guided by a 3D-mapping system measuring LI in addition to GI via an ablation catheter tip with three incorporated mini-electrodes. Local impedance and GI before and during RFC applications were studied. In total, 381 RFC applications were analysed. The baseline LI was higher in high-voltage areas (>0.5 mV; LI: 110.5 ± 13.7 Ω) when compared with intermediate-voltage sites (0.1-0.5 mV; 90.9 ± 10.1 Ω, P < 0.001), low-voltage areas (<0.1 mV; 91.9 ± 16.4 Ω, P < 0.001), and blood pool LI (91.9 ± 9.9 Ω, P < 0.001). During ablation, mean LI drop (△LI; 13.1 ± 9.1 Ω) was 2.15 times higher as mean GI drop (△GI) (6.1 ± 4.2 Ω, P < 0.001). Baseline LI correlated with △LI: a mean LI of 99.9 Ω predicted a △LI of 12.9 Ω [95% confidence interval (12.1-13.6), R2 0.41; P < 0.001]. This relationship was weak for baseline GI predicting △GI (R2 0.06, P < 0.001). Catheter movements were...Continue Reading

References

Jan 1, 1992·Pacing and Clinical Electrophysiology : PACE·M HarveyJ J Langberg
Jan 5, 2001·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·X ZhengR E Ideker
Jan 31, 2006·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Christopher C E LangCarlo Pappone
Jul 16, 2009·Journal of Cardiovascular Electrophysiology·Christopher PiorkowskiGerhard Hindricks
Jul 24, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Vivek Y ReddyKarl-Heinz Kuck
Oct 13, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Thomas GasparChristopher Piorkowski
Nov 2, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Tobias ReichlinGregory F Michaud
Dec 25, 2015·Journal of the American College of Cardiology·Julia VoglerDaniel Steven
Jan 9, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·René van EsFred H M Wittkampf
Jun 24, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ignacio García-BolaoEnrique Vives-Rodríguez
Aug 12, 2017·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Antonio FronteraNicolas Derval
Oct 11, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hugh CalkinsTeiichi Yamane

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Citations

Aug 11, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Paula MünklerChristian Meyer
Aug 11, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Kenneth M SteinTimothy M Stivland
Nov 9, 2019·Journal of Cardiovascular Electrophysiology·Paula MünklerChristian Meyer
Jul 17, 2020·Journal of Cardiovascular Electrophysiology·Masaharu MasudaToshiaki Mano
Jul 8, 2020·Herz·M A GunawardeneS Willems
Nov 21, 2020·Pacing and Clinical Electrophysiology : PACE·Kohki NakamuraShigeto Naito
Feb 8, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Moloy DasIgnacio García-Bolao
Feb 23, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Hidehiro IwakawaTetsuo Sasano
Mar 24, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Shinsuke MiyazakiHiroshi Tada
Apr 15, 2021·Journal of Cardiovascular Electrophysiology·Gavin S Chu, Dhiraj Gupta
Jun 30, 2021·Journal of Cardiovascular Electrophysiology·Daisuke KawanoKazuo Matsumoto
Jul 6, 2021·Journal of Cardiovascular Electrophysiology·Kofi OseiJason Meyers
Oct 5, 2021·Pacing and Clinical Electrophysiology : PACE·Francesco SolimeneLuca Segreti
Dec 19, 2021·Journal of Cardiovascular Electrophysiology·Gavin S ChuDhiraj Gupta

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