A novel bioimpedance technique to monitor fluid volume state during hemodialysis treatment

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
G MedranoS Leonhardt

Abstract

Bioimpedance spectroscopy is a potential candidate for monitoring of body fluids during dialysis. In this article, the suitability of knee-to-knee (KK) as an alternative to wrist-to-ankle (WA) bioimpedance spectroscopy measurements during dialysis is evaluated. Measurements on eight patients (22 dialysis sessions) showed a good correlation between the change in extracellular resistance (Re) in KK and WA measurements. A deeper analysis indicated that the change in Re normalized for ultrafiltrated volume [DeltaRe/UFV (%/L)] depends on the characteristics of the patient: clinically stable patients [with a presumed lower extracellular fluid - total body volume (VB) relationship] show a higher DeltaRe/UFV (%/L) mean +/- standard deviation (WA: 8.90 +/- 1.9 and KK: 8.29 +/- 2.2) than clinically unstable patients with pitting peripheral edema (WA: 2.10 +/- 0.8 and KK: 2.07 +/- 0.2). Simulations based on bioimpedance equations considering Hanai theory confirm the results. The KK method, especially in combination with proper use of the introduced DeltaRe/UFV (%/L) normalization could possibly offer new options for comfortable online monitoring and the evaluation of fluid volume state during dialysis.

Associated Clinical Trials

References

Sep 1, 1996·The American Journal of Clinical Nutrition·R F KushnerD A Schoeller
May 1, 1997·Journal of Applied Physiology·A De LorenzoP Withers
Mar 1, 1997·Medical & Biological Engineering & Computing·H ScharfetterH Hutten
Sep 22, 2001·The American Journal of Clinical Nutrition·F Slinde, L Rossander-Hulthén
Dec 4, 2001·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·T ShulmanR M Lindsay
May 25, 2002·Kidney International·Paul W ChamneyVolker Wizemann
Jun 12, 2002·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·P L M Cox-ReijvenP B Soeters
Jun 13, 2002·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Michel Y JaffrinMichel Tolani
Jan 16, 2004·IEEE Transactions on Bio-medical Engineering·Marianne Fenech, Michel Y Jaffrin
Jun 3, 2004·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Michael ZellwegerFrançois Madore
Jun 12, 2004·Medical & Biological Engineering & Computing·K SakamotoN Furuya
Mar 25, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Judith J DasselaarCasper F M Franssen
Jul 27, 2006·Physiological Measurement·Ulrich M MoisslNigel J Fuller
Jan 9, 2007·The American Journal of Clinical Nutrition·Paul W ChamneyNigel J Fuller

❮ Previous
Next ❯

Citations

Apr 21, 2010·Medical & Biological Engineering & Computing·Guillermo MedranoSteffen Leonhardt
Jan 18, 2013·European Journal of Clinical Nutrition·J C MárquezK Lindecrantz
May 17, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Abdul Hamid IsmailSteffen Leonhardt
Apr 8, 2015·PloS One·Wojciech DąbrowskiDaniel Schneditz
Oct 18, 2014·Biomedizinische Technik. Biomedical Engineering·Thomas SchlebuschSteffen Leonhardt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.