A novel depth-of-interaction block detector for positron emission tomography using a dichotomous orthogonal symmetry decoding concept

Physics in Medicine and Biology
Yuxuan ZhangWai-Hoi Wong

Abstract

Conventionally, a dual-end depth-of-interaction (DOI) block detector readout requires two two-dimensional silicon photomultiplier (SiPM) arrays, one on top and one on the bottom, to define the XYZ positions. However, because both the top and bottom SiPM arrays are reading the same pixels, this creates information redundancy. We propose a dichotomous orthogonal symmetric (DOS) dual-end readout block detector design, which removes this redundancy by reducing the number of SiPMs and still achieves XY and DOI (Z) decoding for positron emission tomography (PET) block detector. Reflecting films are used within the block detector to channel photons going to the top of the block to go only in the X direction, and photons going to the bottom are channeled along the Y direction. Despite the unidirectional channeling on each end, the top readout provides both X and Y information using two one-dimensional SiPM arrays instead of a two-dimensional SiPM array; similarly, the bottom readout also provides both X and Y information with just two one-dimensional SiPM arrays. Thus, a total of four one-dimensional SiPM arrays (4  ×  N SiPMs) are used to decode the XYZ positions of the firing pixels instead of two two-dimensional SiPM arrays (2  ×  N...Continue Reading

References

Feb 11, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Valentino BettinardiFerruccio Fazio
Nov 24, 2004·Physics in Medicine and Biology·S JanC Morel
Nov 24, 2004·Physics in Medicine and Biology·Kisung LeeTom K Lewellen
Mar 15, 2006·Medical Physics·Sara St James, Christopher J Thompson
Jul 11, 2006·IEEE Transactions on Medical Imaging·Vladimir Y PaninMichael Casey
Mar 5, 2009·Physics in Medicine and Biology·Huini DuSimon R Cherry
Mar 7, 2009·Physics in Medicine and Biology·Marnix C MaasCarel W E van Eijk
Jun 1, 2008·IEEE Transactions on Nuclear Science·Rocio A RamirezWai-Hoi Wong
Feb 13, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ludovic Le MeunierDaniel S Berman
Jul 6, 2010·Physics in Medicine and Biology·E RapisardaM C Gilardi
Aug 13, 2010·Physics in Medicine and Biology·C CloquetS Goldman
Mar 24, 2011·Physics in Medicine and Biology·B W JakobyD W Townsend
May 26, 2011·Physics in Medicine and Biology·L R MacDonaldP E Kinahan
Oct 6, 2011·Physics in Medicine and Biology·Taiga YamayaMitsuo Watanabe
Oct 14, 2011·Medical Physics·V BettinardiM C Gilardi
Dec 16, 2011·Physics in Medicine and Biology·Seiichi YamamotoJun Hatazawa
Jun 9, 2012·Physics in Medicine and Biology·Jonathan K PoonRamsey D Badawi
Sep 22, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Wai-Hoi WongShaohui An
Oct 23, 2012·Nuclear Instruments & Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment·Chad Bircher, Yiping Shao
May 31, 2013·Medical Physics·Arman RahmimVesna Sossi
Jan 10, 2014·IEEE Transactions on Nuclear Science·R I WienerJ S Karp

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Citations

Oct 13, 2016·The British Journal of Radiology·Stephan WalrandFrançois Jamar
Jul 2, 2016·Physics in Medicine and Biology·Jeffrey P SchmallSuleman Surti
Oct 22, 2020·Physics in Medicine and Biology·Junwei DuSimon R Cherry

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