PMID: 9555910Apr 29, 1998Paper

A novel DNA polymerase family found in Archaea

Journal of Bacteriology
Y IshinoY Koga

Abstract

One of the most puzzling results from the complete genome sequence of the methanogenic archaeon Methanococcus jannaschii was that the organism may have only one DNA polymerase gene. This is because no other DNA polymerase-like open reading frames (ORFs) were found besides one ORF having the typical alpha-like DNA polymerase (family B). Recently, we identified the genes of DNA polymerase II (the second DNA polymerase) from the hyperthermophilic archaeon Pyrococcus furiosus, which has also at least one alpha-like DNA polymerase (T. Uemori, Y. Sato, I. Kato, H. Doi, and Y. Ishino, Genes Cells 2:499-512, 1997). The genes in M. jannaschii encoding the proteins that are homologous to the DNA polymerase II of P. furiosus have been located and cloned. The gene products of M. jannaschii expressed in Escherichia coli had both DNA polymerizing and 3'-->5' exonuclease activities. We propose here a novel DNA polymerase family which is entirely different from other hitherto-described DNA polymerases.

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Citations

Nov 25, 1998·Proceedings of the National Academy of Sciences of the United States of America·I K CannY Ishino
Jul 15, 2006·Nucleosides, Nucleotides & Nucleic Acids·Sonoko Ishino, Yoshizumi Ishino
Jan 16, 2009·Biochemical Society Transactions·Stuart A MacNeill
Mar 30, 2020·Nature Communications·Clément MadruLudovic Sauguet
Nov 1, 2000·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·E Warbrick
Sep 17, 2013·Nature Reviews. Microbiology·Sonja-Verena AlbersChrista Schleper
May 6, 2014·Extremophiles : Life Under Extreme Conditions·Lucia GreenoughAndrew F Gardner
Oct 10, 1998·Molecular Microbiology·R Bernander
Oct 7, 2003·Annual Review of Microbiology·Beatrice Grabowski, Zvi Kelman
Sep 16, 2008·Applied and Environmental Microbiology·Jeong Jin ChoiSuk-Tae Kwon
Feb 26, 2009·Nucleic Acids Research·Lars SchomacherHans-Joachim Fritz
Mar 19, 2013·Journal of Bacteriology·Lubomira CubonováThomas J Santangelo
Sep 2, 2014·Frontiers in Microbiology·Melissa Castillo-LizardoEnrique Viguera
May 23, 2014·Frontiers in Microbiology·Tom KilleleaGhislaine Henneke
Aug 14, 1999·Nucleic Acids Research·D D LeipeE V Koonin
Aug 1, 1998·Nucleic Acids Research·L Aravind, E V Koonin
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Sep 16, 2014·Frontiers in Microbiology·Sonoko Ishino, Yoshizumi Ishino
Jun 7, 2020·Annual Review of Microbiology·Mark D Greci, Stephen D Bell
May 4, 2017·Nature Communications·Jiangyu YanStephen D Bell
May 2, 2018·Frontiers in Molecular Biosciences·Katsuya DaimonYoshizumi Ishino
May 28, 2003·Extremophiles : Life Under Extreme Conditions·Sonoko IshinoYoshizumi Ishino
Dec 7, 2018·Extremophiles : Life Under Extreme Conditions·Natsuki TakashimaYoshizumi Ishino
Jan 17, 2019·Biochemical Society Transactions·Pierre RaiaLudovic Sauguet
Dec 2, 2020·Open Biology·Patricia Pérez-ArnaizThorsten Allers
Dec 14, 2018·Emerging Topics in Life Sciences·Christopher D O Cooper

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