A novel experimental approach for nanostructure analysis: simultaneous small-angle X-ray and neutron scattering

Journal of Applied Crystallography
Ezzeldin MetwalliTobias Unruh

Abstract

Exploiting small-angle X-ray and neutron scattering (SAXS/SANS) on the same sample volume at the same time provides complementary nanoscale structural information in two different contrast situations. Unlike an independent experimental approach, the truly combined SAXS/SANS experimental approach ensures the exactness of the probed samples, particularly for in situ studies. Here, an advanced portable SAXS system that is dimensionally suitable for installation in the D22 zone of ILL is introduced. The SAXS apparatus is based on a Rigaku switchable copper/molybdenum microfocus rotating-anode X-ray generator and a DECTRIS detector with a changeable sample-to-detector distance of up to 1.6 m in a vacuum chamber. A case study is presented to demonstrate the uniqueness of the newly established method. Temporal structural rearrangements of both the organic stabilizing agent and organically capped gold colloidal particles during gold nanoparticle growth are simultaneously probed, enabling the immediate acquisition of correlated structural information. The new nano-analytical method will open the way for real-time investigations of a wide range of innovative nanomaterials and will enable comprehensive in situ studies on biological system...Continue Reading

References

May 9, 2000·The Journal of Biological Chemistry·D I Svergun, K H Nierhaus
May 4, 2002·Annual Review of Biophysics and Biomolecular Structure·Joachim Frank
Sep 30, 2004·International Journal of Pharmaceutics·Andreas Illing, Tobias Unruh
Oct 27, 2010·Journal of Synchrotron Radiation·Malene Hillerup JensenBente Vestergaard
Jun 21, 2011·Journal of Synchrotron Radiation·Wenjun LiuJ Y Choi
Dec 12, 2012·Annual Review of Physical Chemistry·Clement E Blanchet, Dmitri I Svergun
Jun 26, 2013·Acta Crystallographica. Section D, Biological Crystallography·Tadeusz Skarzynski
Oct 15, 2013·Journal of Synchrotron Radiation·Rita GraceffaThomas C Irving
Oct 15, 2013·Nature·Audrone LapinaiteTeresa Carlomagno
Jun 9, 2014·The Journal of Chemical Physics·Martin SchmieleTobias Unruh
Jul 6, 2014·Nucleic Acids Research·Yujie ChenLois Pollack
Sep 10, 2014·The Journal of Physical Chemistry. B·Simone GehrerTobias Unruh
Jun 23, 2015·Physical Chemistry Chemical Physics : PCCP·Martin SchmieleFrank Steiniger
Aug 12, 2015·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Ezzeldin MetwalliPeter Müller-Buschbaum
Sep 4, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·T SchindlerT Unruh
Oct 27, 2015·Journal of Applied Crystallography·Ingo BreßlerAndreas F Thünemann
May 28, 2016·The Journal of Physical Chemistry. B·M SchmieleT Unruh
Dec 17, 2016·Journal of Applied Crystallography·Ashley JordanAnne Martel
Feb 9, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Francesco SpinozziPaolo Ghigna
Jun 6, 2017·Journal of Colloid and Interface Science·Torben SchindlerTobias Unruh
Jun 14, 2018·Journal of Applied Crystallography·Carlos G LopezJoão T Cabral
Nov 15, 2018·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Tilo SchmutzlerTobias Unruh
Dec 14, 2018·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Moritz H FutscherNorbert Koch
Sep 25, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Isabel SchuldesTobias Unruh

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Citations

Apr 28, 2021·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Fabrizia FogliaPaul F McMillan

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Methods Mentioned

BETA
SANS
transmission electron microscopy
X-ray

Software Mentioned

SANS
ILL
SAS
EIGER
Dectris
NOMAD
NICOS Zentrum ( MLZ )
TANGO
NICOS
Network Based Instrument Control System ( NICOS )

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