A novel family of calmodulin-binding transcription activators in multicellular organisms.

The Journal of Biological Chemistry
Nicolas BouchéHillel Fromm

Abstract

Screening of cDNA expression libraries derived from plants exposed to stress, with 35S-labeled recombinant calmodulin as a probe, revealed a new family of proteins containing a transcription activation domain and two types of DNA-binding domains designated the CG-1 domain and the transcription factor immunoglobulin domain, ankyrin repeats, and a varying number of IQ calmodulin-binding motifs. Based on domain organization and amino acid sequence comparisons, similar proteins, with the same domain organization, were identified in the genomes of other multicellular organisms including human, Drosophila, and Caenorhabditis, whereas none were found in the complete genomes of single cell eukaryotes and prokaryotes. This family of proteins was designated calmodulin-binding transcription activators (CAMTAs). Arabidopsis thaliana contains six CAMTA genes (AtCAMTA1-AtCAMTA6). The transcription activation domain of AtCAMTA1 was mapped by testing a series of protein fusions with the DNA-binding domain of the bacterial LexA transcription factor and two reporter genes fused to LexA recognition sequences in yeast cells. Two human proteins designated HsCAMTA1 and HsCAMTA2 were also shown to activate transcription in yeast using the same report...Continue Reading

References

Jun 14, 1991·Cell·J R GeiserT N Davis
Feb 1, 1990·Trends in Biochemical Sciences·K T O'Neil, W F DeGrado
Oct 1, 1995·Molecular and Cellular Biology·J EstojakE A Golemis
Apr 6, 1995·Biochemical and Biophysical Research Communications·S ZhuangC L Wang
Jan 26, 1995·Nature·C W MüllerS C Harrison
Aug 1, 1994·Plant Molecular Biology·O da Costa e Silva
Apr 1, 1997·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·A R Rhoads, F Friedberg
Oct 1, 1997·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·M G ReeseD Haussler
Jan 31, 1998·Science·P De Koninck, H Schulman
May 28, 1998·Cell Calcium·E K Heist, H Schulman
Feb 27, 1999·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·T NagaseO Ohara
Mar 17, 1999·Nature·A M CarriónJ R Naranjo
Jul 3, 1999·Trends in Biochemical Sciences·P BorkB Snel
Jul 31, 1999·Journal of Chromatography. a·H Gadgil, H W Jarrett
Aug 4, 1999·Trends in Biochemical Sciences·S G Sedgwick, S J Smerdon
Oct 6, 2000·FEBS Letters·A M Rubtsov, O D Lopina
Dec 29, 2000·Nature·UNKNOWN Arabidopsis Genome Initiative
Feb 13, 2001·Biochemical and Biophysical Research Communications·A S ReddyM Golovkin
Mar 10, 2001·Nature·R TuplerM R Green
Mar 10, 2001·Nature·E S LanderUNKNOWN International Human Genome Sequencing Consortium
May 30, 2001·Trends in Plant Science·H Knight, M R Knight
Mar 26, 2002·FEBS Letters·Martin Bähler, Allen Rhoads

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Citations

May 9, 2012·Functional & Integrative Genomics·Sushmita GuptaSudripta Das
Mar 1, 2012·Molecular Biotechnology·Sushmita GuptaSudripta Das
Oct 15, 2003·Trends in Plant Science·Tianbao Yang, B W Poovaiah
Mar 6, 2003·Cellular Signalling·Danton H O'Day
Jan 24, 2009·Proceedings of the National Academy of Sciences of the United States of America·Dazhi LaiTian Chi
Dec 12, 2012·Proceedings of the National Academy of Sciences of the United States of America·Stephen MallonBernard Roizman
May 31, 2008·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Shusei SatoSatoshi Tabata
Dec 28, 2011·Journal of Experimental Botany·Simon StaelMarkus Teige
May 3, 2005·Annual Review of Plant Biology·Nicolas BouchéHillel Fromm
Apr 4, 2013·BMC Genomics·Neha PandeySamir V Sawant
Jun 21, 2012·PloS One·Barbara Muller-BorerNadia N Malouf
Jul 23, 2014·Proceedings of the National Academy of Sciences of the United States of America·Chengzu LongEric N Olson
Aug 12, 2014·Expert Review of Molecular Diagnostics·Meera Hameed
Mar 1, 2005·FEBS Letters·Chan Young ParkMoo Je Cho
Aug 11, 2007·FEBS Letters·Aliza FinklerHillel Fromm
Jun 26, 2015·Journal of Integrative Plant Biology·Marta BjornsonKatayoon Dehesh
Feb 18, 2014·The Plant Journal : for Cell and Molecular Biology·Lei ZhangB W Poovaiah
Jun 21, 2011·Biochimie·Christian MazarsPatrice Thuleau
Mar 15, 2016·Frontiers in Plant Science·Hafizur RahmanXin-Zhong Cai
Jan 16, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Kai-Oliver HenrichFrank Westermann
Oct 10, 2015·Applied Microbiology and Biotechnology·Chenjia ShenHuizhong Wang
Nov 4, 2015·Frontiers in Plant Science·Amardeep S VirdiPrabhjeet Singh
Sep 14, 2004·The Plant Journal : for Cell and Molecular Biology·Tou Cheu XiongChristian Mazars
Jun 18, 2005·The Plant Journal : for Cell and Molecular Biology·Maggie LevySteffen Abel
Dec 9, 2014·Plant Signaling & Behavior·Lei ZhangB W Poovaiah

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