A novel finding on computed tomography in the diagnosis and localization of cerebrospinal fluid leaks without a clear bony defect

International Forum of Allergy & Rhinology
R Peter ManesBradley F Marple

Abstract

The purpose of this work was to describe a clinical and radiographic pattern of findings that helps localize the site of spontaneous cerebrospinal fluid (CSF) leaks. This study was a retrospective review of CSF leaks treated at the University of Texas Southwestern Medical Center from 2000 to 2009. Data collected included demographics, nature of presentation, imaging findings, intraoperative location of skull-base defect, and clinical follow-up. Forty-six patients' charts were reviewed. Among these patients, 15 did not show a bony skull-base defect on high-resolution computed tomography (CT) scan. They did, however, each show a small area of opacification in the olfactory cleft. In each case, this area of opacification correlated with the site of the CSF leak. Intrathecal fluorescein was not used, except in 2 instances. Successful repair was noted in all patients on follow-up, without evidence of recurrence at the repair site. In the absence of a clearly identifiable bony skull-base defect, opacification of the olfactory cleft is a localizing sign in some cases of spontaneous CSF rhinorrhea. Such a finding should direct endoscopic repair, and may serve as the only marker for the specific leak site.

References

Aug 12, 2006·The Annals of Otology, Rhinology, and Laryngology·Rodney J SchlosserWilliam E Bolger

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Citations

Aug 5, 2014·Neuroimaging Clinics of North America·Kristen L Baugnon, Patricia A Hudgins
Sep 16, 2015·International Forum of Allergy & Rhinology·Gretchen M OakleyRichard R Orlandi
Mar 19, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Imen GharzouliPhilippe Herman
Dec 3, 2014·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Shawn M StevensTed A Meyer
Feb 26, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Shawn M StevensTed A Meyer
Jun 22, 2018·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·E V SheleskoD N Zinkevich

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