A novel gene cluster soxSRT is essential for the chemolithotrophic oxidation of thiosulfate and tetrathionate by Pseudaminobacter salicylatoxidans KCT001

Current Microbiology
Chandrajit LahiriPradosh Roy

Abstract

Chemolithotrophic sulfur oxidation (Sox) in the alpha-proteobacterium Pseudaminobacter salicylatoxidans KCT001 was found to be governed by the gene cluster soxSRT-soxVWXYZABCD. Independent transposon-insertion mutations in the genes soxB, soxC, soxD, and also in a novel open reading frame (ORF), designated as soxT, afforded revelation of the entire sox locus of this bacterium. The deduced amino acid sequence of the novel ORF soxT comprised 362 residues and exhibited significant homology with hypothetical proteins of diverse origin, including a permease-like transport protein of Escherichia coli. Two contiguous ORFs, soxR and soxS, immediately preceded the soxT gene. The gene cluster soxSRT was located upstream of soxVWXYZABCD and was transcribed divergently with respect to the latter. Chemolithotrophic utilization of both thiosulfate and tetrathionate was observed to have been impaired in all of these Sox- mutants, implicating the involvement of the gene cluster soxSRT-soxVWXYZABCD in the oxidation of both thiosulfate and tetrathionate.

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Citations

Jan 14, 2010·Applied Biochemistry and Biotechnology·Kishore Kumar KrishnaniS M Pillai
May 21, 2013·Applied and Environmental Microbiology·Masrure AlamWriddhiman Ghosh
Sep 28, 2007·Canadian Journal of Microbiology·R AnandhamTongmin Sa
Oct 1, 2007·Pakistan Journal of Biological Sciences : PJBS·Mojtaba TahmoorespurShahrokh Ghovvati
Apr 7, 2012·Archives of Microbiology·Sukhendu Mandal, Sujoy K Das Gupta
Oct 5, 2019·Microbiological Research·Moidu Jameela RameezWriddhiman Ghosh
Jun 22, 2021·FEMS Microbiology Letters·Masrure AlamWriddhiman Ghosh

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