A novel group I intron in Candida dubliniensis is homologous to a Candida albicans intron

Gene
H BoucherG Lemay

Abstract

In the present study, we determined the sequence of group I self-splicing introns found in the large ribosomal RNA subunit of Candida albicans, Candida stellatoidea and the recently-described species Candida dubliniensis. It was found that both the intron and ribosomal RNA nucleotide sequences are almost perfectly identical between different C. albicans strains as well as between C. albicans and C. stellatoidea strains. Comparisons of ribosomal RNA sequences suggest that local isolates of atypical C. albicans from individuals infected with human immunodeficiency virus can be assigned to the C. dubliniensis species. C. dubliniensis strains also harbor a group I intron in their ribosomal RNA, as observed in about 40% of C. albicans strains and all C. stellatoidea strains. This novel C. dubliniensis group I intron is identical to the C. albicans and C. stellatoidea intron, except for two widely divergent stem-loop regions. Despite these differences, the C. dubliniensis intron possesses self-splicing ability in an in vitro assay. Taken together, these data support the idea that C. albicans and C. stellatoidea should be joined together as variants of the same species while C. dubliniensis is a distinct but closely related microorgan...Continue Reading

References

May 11, 1992·Nucleic Acids Research·R R GutellM W Gray
Nov 20, 1992·Journal of Molecular Biology·P T DePriest, M D Been
Jan 1, 1988·Journal of Medical and Veterinary Mycology : Bi-monthly Publication of the International Society for Human and Animal Mycology·F C OddsP D Simmons
Mar 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·S Scherer, D A Stevens
Sep 1, 1994·Nucleic Acids Research·S H Damberger, R R Gutell
Jul 1, 1993·Nucleic Acids Research·R R GutellM N Schnare
Mar 25, 1993·Nucleic Acids Research·S MercureG Lemay

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Citations

Feb 20, 2004·Diagnostic Microbiology and Infectious Disease·Barbara GrafThomas Adam
Jun 19, 2001·Nucleic Acids Research·Y Zhang, M J Leibowitz
Mar 18, 2000·Antimicrobial Agents and Chemotherapy·K E Miletti, M J Leibowitz
Mar 29, 2005·Antimicrobial Agents and Chemotherapy·Matthew D DisneyFrancis Gigliotti
Feb 1, 2000·Emerging Infectious Diseases·M E BrandtR A Hajjeh
Mar 15, 2011·Diagnostic Microbiology and Infectious Disease·Anuradha ChowdharyMary E Brandt
Nov 9, 2004·Chembiochem : a European Journal of Chemical Biology·Matthew D DisneyDouglas H Turner
Jan 6, 2009·The Journal of Eukaryotic Microbiology·Karl E Miletti-González, Michael J Leibowitz
Jul 30, 2010·Mycoses·Orazio Romeo, Giuseppe Criseo
Sep 9, 2004·The Journal of Eukaryotic Microbiology·Oona L O Snoeyenbos-WestLaura A Katz
May 8, 2007·International Journal of Hematology·Kazuhiro Morishita
Nov 23, 2006·Molecular Biology Reports·Prathiba Jayaguru, Malathi Raghunathan
May 11, 1999·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·A VelegrakiN J Legakis
May 14, 1998·Microbiology·Gregor D GilfillanNeil A R Gow
Oct 17, 1998·Journal of Clinical Microbiology·C M ElieC J Morrison
Feb 18, 1998·Journal of Clinical Microbiology·D Sullivan, D Coleman
Jan 5, 2000·Journal of Clinical Microbiology·I PolacheckD C Coleman

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