A novel heme protein that acts as a carbon monoxide-dependent transcriptional activator in Rhodospirillum rubrum

Biochemical and Biophysical Research Communications
Shigetoshi AonoM Okada

Abstract

The gene coding for a carbon monoxide-dependent transcriptional activator (cooA) in Rhodospirillum rubrum has been expressed in E. coli, and the recombinant CooA has been purified. CooA contains b-type heme which may act as a CO sensor in vivo. CO-bound CooA was formed when reduced CooA was reacted with CO, but not in the case of oxidized CooA. CooA is the first example of the heme protein acting as a DNA-binding transcriptional activator.

Citations

Aug 3, 2012·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Aaron T SmithJudith N Burstyn
Jan 17, 2007·Nature Reviews. Microbiology·Gary M King, Carolyn F Weber
May 1, 2012·The Journal of Biological Chemistry·Abdelkrim BenabbasPaul M Champion
Apr 13, 2012·Antioxidants & Redox Signaling·Aisha FarhanaAdrie J C Steyn
May 10, 2006·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Hirofumi KomoriYoshiki Higuchi
Oct 23, 1997·Proceedings of the National Academy of Sciences of the United States of America·D ShelverG P Roberts
Sep 25, 2002·Proceedings of the National Academy of Sciences of the United States of America·Ursula LieblMarten H Vos
Jul 5, 2007·Proceedings of the National Academy of Sciences of the United States of America·Ashwani KumarAdrie J C Steyn
Feb 13, 2007·Journal of Molecular Biology·Hirofumi KomoriYoshiki Higuchi
Oct 4, 2005·Biochemical and Biophysical Research Communications·Tsuneo Omura
Aug 4, 2004·Journal of Molecular Biology·Shuji AkiyamaShigetoshi Aono
Dec 15, 2004·Critical Reviews in Biochemistry and Molecular Biology·Stephen W Ragsdale
May 26, 2006·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Jocelyn C PinkertJudith N Burstyn
Aug 9, 2008·Dalton Transactions : an International Journal of Inorganic Chemistry·Shigetoshi Aono
Apr 4, 2019·Extremophiles : Life Under Extreme Conditions·Yuto FukuyamaYoshihiko Sako
Feb 16, 2005·The Journal of Biological Chemistry·Véronique BallandTony A Mattioli
Mar 31, 2005·The Journal of Biological Chemistry·Takeshi UchidaTeizo Kitagawa
Aug 25, 2004·The Journal of Biological Chemistry·Taku YamashitaTadayuki Uno
Nov 28, 2007·The Journal of Biological Chemistry·Taku YamashitaMarten H Vos
May 11, 2013·The Journal of Biological Chemistry·Bastian MolitorNicole Frankenberg-Dinkel
Sep 25, 1998·The Journal of Biological Chemistry·S AonoH Nakajima
Jan 18, 2006·Accounts of Chemical Research·Yukie SasakuraToru Shimizu
Nov 19, 2003·Accounts of Chemical Research·Shigetoshi Aono
Jun 27, 1998·Biochemical and Biophysical Research Communications·H NakamuraT Iizuka
Jul 17, 1998·Current Opinion in Chemical Biology·S W Ragsdale

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.