A novel high-throughput screening system to evaluate the behavioral response of adult mosquitoes to chemicals

Journal of the American Mosquito Control Association
John P GriecoDonald R Roberts

Abstract

A modular and novel assay system for rapid mass screening of chemical compounds for contact irritant and spatial repellent actions against adult mosquitoes is described. The responses of Aedes aegypti to various concentrations of 3 topical repellents, deet, Bayrepel, and SS220, were evaluated. At treatment concentrations > or = 25 nmol/cm2 of SS220, mosquitoes exhibited significant contact irritant (escape) and spatial repellent (movement away from the chemical source) responses, whereas, a 10-fold increase in the treatment concentration of deet and Bayrepel was required to produce similar responses. The novel bioassay system detected contact irritancy and spatial repellency activity with reproducible results and provided baseline data for determining minimum effective concentrations for other chemicals. The system is compact in size, easy to decontaminate, and requires only a minute quantity of chemical compound.

References

Apr 1, 1987·Medical and Veterinary Entomology·C F CurtisM A Karimzad
Jan 1, 1988·Annual Review of Entomology·K F Haynes
Oct 5, 1983·Journal of Medical Entomology·L C RutledgeG H Eisenberg
Aug 26, 1998·Emerging Infectious Diseases·D J Gubler
Jan 5, 2002·Journal of Medical Entomology·J A KlunM Debboun
May 10, 2002·Trends in Parasitology·Morteza Zaim, Pierre Guillet
Dec 19, 2003·Journal of Medical Entomology·Daniel L KlineDonald R Barnard
Mar 5, 2004·Tropical Medicine & International Health : TM & IH·Athanase BadoloCarlo Costantini
Jun 29, 2004·Journal of Medical Entomology·J A Klun, M Debboun

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Citations

Dec 4, 2013·Parasites & Vectors·Theeraphap ChareonviriyaphapRatchadawan Ngoen-Klan
Jan 31, 2016·Acta Tropica·Rungarun TisgratogTheeraphap Chareonviriyaphap
Nov 28, 2015·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Sunaiyana SathantriphopTheeraphap Chareonviriyaphap
May 14, 2014·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Wanapa RitthisonTheeraphap Chareonviriyaphap
Sep 15, 2010·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Piti MongkalangoonTheeraphap Chareonviriyaphap
Mar 31, 2016·Journal of Medical Entomology·Victor A SugihartoNicole L Achee
Feb 17, 2017·Journal of the American Mosquito Control Association·Michaël FalkowskiIsabelle Dusfour
Feb 22, 2017·Annals of the New York Academy of Sciences·Kim L Vertacnik, Catherine R Linnen
Mar 7, 2009·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Suppaluck PolsomboonTheeraphap Chareonviriyaphap
Sep 15, 2010·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Isabelle DusfourJohn P Grieco
Mar 26, 2019·Medical and Veterinary Entomology·S JiangJ R Bloomquist
Oct 23, 2008·Journal of the American Mosquito Control Association·Nancy McLean-CooperJack Williams
Aug 6, 2009·Journal of the American Mosquito Control Association·Nicole L AcheeJohn P Grieco
Jul 20, 2016·PLoS Neglected Tropical Diseases·Diane B ChoiNicole L Achee
Sep 26, 2020·PLoS Computational Biology·Quirine A Ten BoschT Alex Perkins
Jan 27, 2010·Journal of the American Mosquito Control Association·Sukhaynah H SaidNicole L Achee
Oct 25, 2011·Journal of the American Mosquito Control Association·Naritsara MalaithongTheeraphap Chareonviriyaphap
Mar 15, 2019·Parasites & Vectors·Emilie DeletreFabrice Chandre
Oct 14, 2010·Journal of Medical Entomology·Naritsara MalaithongTheeraphap Chareonviriyaphap
Apr 7, 2015·Journal of the American Mosquito Control Association·Steven DenhamKarla Saavedra-Rodriguez
Jun 10, 2016·Journal of the American Mosquito Control Association·Alongkot PonlawatBrian P Evans
May 21, 2020·The American Journal of Tropical Medicine and Hygiene·Din SyafruddinNicole L Achee
Oct 14, 2017·Journal of Medical Entomology·Rungarun TisgratogTheeraphap Chareonviriyaphap
Oct 21, 2020·Journal of Medical Entomology·Chutipong SukkanonTheeraphap Chareonviriyaphap
Apr 17, 2021·Natural Product Research·Natalia Mendes Gomes MagalhaesLaila Salmen Espindola

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Methods Mentioned

BETA
Assay

Software Mentioned

SAS

Related Concepts