A novel importin alpha from rice, a component involved in the process of nuclear protein transport

FEBS Letters
T IwasakiN Yamamoto

Abstract

In eukaryotes, nuclear proteins that are transported into nuclei have nuclear localization signals (NLSs), which are recognized by proteins called importin alpha. We isolated a rice cDNA, #61L, and the corresponding gene that encodes a protein, which shows significant homology to the importin alpha. Although the encoded protein had only 23-27% amino acid identity to the importin alphas from various organisms including plants, the fusion protein with glutathione S-transferase showed a specific binding activity to the NLS of SV40 T-antigen. These results suggest that the rice #61L protein is a novel importin alpha in plants.

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Citations

Oct 20, 1999·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·N Yamamoto, X W Deng
Mar 10, 2007·The Plant Journal : for Cell and Molecular Biology·Thirumala-Devi KannegantiSaskia A Hogenhout

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