A Novel In Situ Toxicity Identification Evaluation (iTIE) System for Determining which Chemicals Drive Impairments at Contaminated Sites

Environmental Toxicology and Chemistry
G Allen BurtonGunther Rosen

Abstract

Human-dominated waterways contain thousands of chemicals. Determining which chemical is the most important stressor is important, yet very challenging. The Toxicity Identification Evaluation (TIE) procedure from the US Environmental Protection Agency uses a series of chemical and physical manipulations to fractionate compounds within a matrix and systematically identify potential toxicants through laboratory bioassay testing. Although this may provide useful information, it lacks ecological realism because it is subject to laboratory-related artifacts and is resource intensive. The in situ Toxicity Identification Evaluation (iTIE) technology was developed to improve this approach and has undergone a number of modifications over the past several years. The novel prototype 3 consists of an array of iTIE ambient water fractionation units. Each unit is connected to a peristaltic pumping system with an organism exposure chamber that receives water from a resin chamber to chemically fractionate test site water. Test organisms included freshwater and marine standard toxicity test species. Postfractionation waters are collected for subsequent chemical analyses. Currently, the resins allow for separation of ammonia, metals, and nonpolar...Continue Reading

References

Jan 15, 2005·Environmental Toxicology and Chemistry·G Allen Burton, Juanita E Nordstrom
Jan 15, 2005·Environmental Toxicology and Chemistry·G Allen Burton, Juanita F Nordstrom
Feb 9, 2010·Ecotoxicology and Environmental Safety·Brian S AndersonAbdou Mekebri
Aug 24, 2013·Environmental Toxicology and Chemistry·Kay T Ho, Robert M Burgess
Nov 26, 2016·Environmental Toxicology and Chemistry·August J SteigmeyerG Allen Burton

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