A novel L-arabinose-responsive regulator discovered in the rice-blast fungus Pyricularia oryzae (Magnaporthe oryzae)

FEBS Letters
Sylvia KlaubaufEvy Battaglia

Abstract

In this study we identified the L-arabinose-responsive regulator of Pyricularia oryzae that regulates L-arabinose release and catabolism. Previously we identified the Zn2Cys6 transcription factor (TF) AraR that has this role in the Trichocomaceae family (Eurotiales), but is absent in other fungi. Candidate Zn2Cys6 TF genes were selected according to their transcript profiles on L-arabinose. Deletion mutants of these genes were screened for their growth phenotype on L-arabinose. One mutant, named Δara1, was further analyzed. Our analysis demonstrated that Ara1 from P. oryzae is the functional analog of AraR from A. niger, while there is no significant sequence similarity between them. This article is protected by copyright. All rights reserved.

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Citations

Jan 4, 2018·International Journal of Molecular Sciences·Muhammad AdnanGuodong Lu
Jan 30, 2019·Applied Microbiology and Biotechnology·Kevin SchmitzJ Philipp Benz
Jun 16, 2017·Biotechnology for Biofuels·Tiziano BenocciRonald P de Vries
Oct 6, 2019·Applied and Environmental Microbiology·Paul DalyRonald P de Vries
Mar 1, 2020·Proceedings of the National Academy of Sciences of the United States of America·Vincent W WuN Louise Glass
Jun 26, 2021·Proceedings of the National Academy of Sciences of the United States of America·Raphael GabrielJ Philipp Benz

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