A novel lactic acid bacterium for the production of high purity L-lactic acid, Lactobacillus paracasei subsp. paracasei CHB2121

Journal of Bioscience and Bioengineering
Se-Kwon MoonGi-Wook Choi

Abstract

Fermentation-derived lactic acid has several potential industrial uses as an intermediate carbon chemical and a raw material for biodegradable polymer. We therefore undertook the identification of a novel bacterial strain that is capable of producing high concentrations of lactic acid and has potential commercial applications. A novel L(+)-lactic acid producing bacterium, Lactobacillus paracasei subsp. paracasei CHB2121 was isolated from soil obtained near an ethanol production factory and identified by 16S rRNA gene sequence analysis and characterization using an API 50 CHL kit. L. paracasei subsp. paracasei CHB2121 efficiently produced 192 g/L lactic acid from medium containing 200 g/L of glucose, with 3.99 g/(L·h) productivity, and 0.96 g/g yield. In addition, the optical purity of the produced lactic acid was estimated to be 96.6% L(+)-lactic acid. The newly identified L. paracasei subsp. paracasei CHB2121 efficiently produces high concentrations of lactic acid, and may be suitable for use in the industrial production of lactic acid.

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Citations

Apr 30, 2013·Biotechnology Advances·Mohamed Ali Abdel-RahmanKenji Sonomoto
Aug 29, 2014·Journal of Industrial Microbiology & Biotechnology·Se-Kwon MoonGi-Wook Choi
Jul 2, 2014·Biotechnology and Bioengineering·Robert D HoelzleDamien J Batstone
Jan 7, 2015·Journal of Bioscience and Bioengineering·Yixing Zhang, Praveen V Vadlani
Aug 1, 2014·Journal of Bioscience and Bioengineering·Ying WangKenji Sonomoto
Jan 10, 2020·Current Pharmaceutical Biotechnology·Huey-Chun HuangTsong-Min Chang
Aug 8, 2020·Frontiers in Microbiology·Andrea ComasioLuc De Vuyst
Oct 23, 2020·Heliyon·Elahe Abedi, Seyed Mohammad Bagher Hashemi
Aug 21, 2021·Critical Reviews in Biotechnology·Ernesta AugustinieneNaglis Malys

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