A novel Meloidogyne enterolobii effector MeTCTP promotes parasitism by suppressing programmed cell death in host plants

Molecular Plant Pathology
Kan ZhuoJinling Liao

Abstract

Meloidogyne enterolobii is one of the most important plant-parasitic nematodes that can overcome the Mi-1 resistance gene and damage many economically important crops. Translationally controlled tumour protein (TCTP) is a multifunctional protein that exists in various eukaryotes and plays an important role in parasitism. In this study, a novel M. enterolobii TCTP effector, named MeTCTP, was identified and functionally characterized. MeTCTP was specifically expressed within the dorsal gland and was up-regulated during M. enterolobii parasitism. Transient expression of MeTCTP in protoplasts from tomato roots showed that MeTCTP was localized in the cytoplasm of the host cells. Transgenic Arabidopsis thaliana plants overexpressing MeTCTP were more susceptible to M. enterolobii infection than wild-type plants in a dose-dependent manner. By contrast, in planta RNA interference (RNAi) targeting MeTCTP suppressed the expression of MeTCTP in infecting nematodes and attenuated their parasitism. Furthermore, MeTCTP could suppress programmed cell death triggered by the pro-apoptotic protein BAX. These results demonstrate that MeTCTP is a novel plant-parasitic nematode effector that promotes parasitism, probably by suppressing programmed ce...Continue Reading

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Citations

Nov 2, 2019·Communicative & Integrative Biology·Rosita Grijalva-MañayVinicio Armijos-Jaramillo
Mar 17, 2020·Frontiers in Plant Science·Araceli LamelasGloria Carrión
Oct 17, 2019·Frontiers in Plant Science·Kazuki SatoKen Shirasu
Jun 6, 2017·Frontiers in Plant Science·Sagar BanerjeeAnil Sirohi
Mar 29, 2019·Current Opinion in Plant Biology·Paulo Vieira, Cynthia Gleason

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