A novel minimally invasive near-infrared thoracoscopic localization technique of small pulmonary nodules: A phase I feasibility trial

The Journal of Thoracic and Cardiovascular Surgery
Hideki UjiieKazuhiro Yasufuku

Abstract

Localization and resection of nonvisible, nonpalpable pulmonary nodules during video-assisted thoracoscopic surgery are challenging. Our study was to determine the feasibility and safety of indocyanine green fluorescence localization and resection of small nodules using a near-infrared fluorescence thoracoscope. Twenty patients with undiagnosed peripheral nodules smaller than 3 cm scheduled for computed tomography-guided microcoil placement followed by video-assisted thoracoscopic surgery wedge resection were enrolled. After microcoil deployment, 100 to 150 μL of diluted indocyanine green was injected percutaneously near the nodule. The nodule initially was localized solely by using a near-infrared thoracoscope to visualize indocyanine green fluorescence. Thoracoscopic instruments were used to determine the staple line. Wedge resection was performed after confirmation of the location of the microcoil using fluoroscopy. Twenty patients underwent near-infrared, image-guided, video-assisted thoracoscopic surgery resection. The median computed tomography tumor size was 1.2 cm. The median depth from the pleural surface was 1.4 cm (range, 0.2-4.8 cm). The median computed tomography-guided intervention time was 35 minutes, and video-a...Continue Reading

Citations

Nov 14, 2017·Future Oncology·Keyvan Moghissi, Kate Dixon
Feb 9, 2019·Thoracic Cancer·Chao ZhangWen-Zhao Zhong
May 6, 2019·Expert Review of Respiratory Medicine·Hideki UjiieKazuhiro Yasufuku
May 28, 2019·Surgery Today·Junji IchinoseSakae Okumura
Jun 28, 2019·Pediatric Surgery International·C T LauK K Y Wong
Oct 14, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Olugbenga T OkusanyaInderpal S Sarkaria
Jul 31, 2020·Journal of Cardiothoracic Surgery·Chu-Chun LiangBing-Yen Wang
Oct 31, 2020·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Katie N CornellaLauren E Openshaw
Feb 12, 2020·Postgraduate Medical Journal·Long-Long WangJia-Yuan Sun
Oct 29, 2020·Journal of Pediatric Surgery·Katrina M MorganMarcus M Malek
Mar 14, 2019·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Chi-Wei LinYeun-Chung Chang
Dec 24, 2019·The Journal of Thoracic and Cardiovascular Surgery·Liwen FanFeng Yao

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