A novel moisturizer with high sun protection factor improves cutaneous barrier function and the visible appearance of rosacea-prone skin

Journal of Cosmetic Dermatology
H E BaldwinSandrine Teissedre

Abstract

Consensus guidelines advocate general skincare for rosacea patients. Two independent studies were performed to assess whether a tinted daily SPF-30 facial moisturizer (DFM30) improves barrier function of dry skin and the efficacy and tolerability of DFM30 on rosacea-prone skin. In study 1, electrical capacitance (EC) and transepidermal water loss (TEWL) were measured at baseline, 2, 4, 8, and 24 hours after a single application of DFM30 and on a control site in 21 healthy females with dry skin. Study 2 evaluated 33 females with mild to moderate rosacea and nontransient erythema. Efficacy and tolerability after once-daily DFM30 were assessed using a chromameter, image analysis of photographs, and trained rater and patient evaluations up to day 22. In study 1, EC showed statistically significant increases at 2, 4, and 8 hours, and TEWL showed statistically significant decreases 2, 4, 8, and 24 hours after DFM30 application to healthy females compared to baseline. In study 2, covering skin redness improved significantly after DFM30 application on day 1; 33.3% showed improved covering skin redness compared to baseline. Patients reported significantly less redness on day 8 than day 3. Feelings of dryness and tightness/tension were l...Continue Reading

References

Jul 6, 2014·Journal of the American Academy of Dermatology·Farah MoustafaSteven R Feldman
Oct 2, 2014·Acta Dermato-venereologica·Mireille M D van der LindenJohn de Korte
Mar 18, 2016·Anais Brasileiros De Dermatologia·Flavia Alvim Sant'Anna Addor
Mar 18, 2016·Dermatology and Therapy·Anthony BewleyVincent Rives
Nov 16, 2016·Skin Appendage Disorders·Manal Abokwidir, Steven R Feldman
Nov 20, 2016·The British Journal of Dermatology·M SchallerJ Tan

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Citations

May 6, 2020·Clinical, Cosmetic and Investigational Dermatology·Daniele MaggioniClaudio Angelinetta
Nov 11, 2020·Dermatology and Therapy·Hanlin ZhangQiuning Sun
Feb 25, 2021·Journal of Cosmetic Dermatology·Daniel Morgado-CarrascoJaime Piquero-Casals
Oct 14, 2021·Acta Dermato-venereologica·Martin SchallerJames Del Rosso

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Methods Mentioned

BETA
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Software Mentioned

ProDerm
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