A Novel Phage Infecting Alteromonas Represents a Distinct Group of Siphophages Infecting Diverse Aquatic Copiotrophs.

MSphere
Ruijie MaRui Zhang

Abstract

Bacteriophages play critical roles in impacting microbial community succession both ecologically and evolutionarily. Although the majority of phage genetic diversity has been increasingly unveiled, phages infecting members of the ecologically important genus Alteromonas remain poorly understood. Here, we present a comprehensive analysis of a newly isolated alterophage, vB_AcoS-R7M (R7M), to characterize its life cycle traits, genomic features, and putative evolutionary origin. R7M harbors abundant genes identified as host-like auxiliary metabolic genes facilitating viral propagation. Genomic analysis suggested that R7M is distinct from currently known alterophages. Interestingly, R7M was found to share a set of similar characteristics with a number of siphophages infecting diverse aquatic opportunistic copiotrophs. We therefore proposed the creation of one new subfamily (Queuovirinae) to group with these evolutionarily related phages. Notably, tail genes were less likely to be shared among them, and baseplate-related genes varied the most. In-depth analyses indicated that R7M has replaced its distal tail with a Rhodobacter capsulatus gene transfer agent (RcGTA)-like baseplate and further acquired a putative receptor interaction...Continue Reading

References

Sep 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·M P Conley, W B Wood
Jan 1, 1974·Intervirology·H W Ackermann, A Eisenstark
May 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·R S Lloyd, P C Hanawalt
Apr 1, 1997·Applied and Environmental Microbiology·M FurutaJ L Van Etten
Mar 3, 1999·Proceedings of the National Academy of Sciences of the United States of America·R W HendrixG F Hatfull
Mar 11, 2003·Microbiology and Molecular Biology Reviews : MMBR·Eric S MillerWolfgang Rüger
Apr 28, 2004·FEMS Microbiology Reviews·Markus G Weinbauer
Apr 26, 2005·Nucleic Acids Research·Yang Zhang, Jeffrey Skolnick
Aug 2, 2005·Nature·Marcel MarguliesJonathan M Rothberg
Jan 5, 2006·Molecular Microbiology·Miryam GrossGad Glaser
Nov 17, 2006·Environmental Microbiology·Martha R J Clokie, Nicholas H Mann
Dec 1, 2006·Nucleic Acids Research·Aron Marchler-BauerStephen H Bryant
Sep 15, 2007·Nature Reviews. Microbiology·Curtis A Suttle
Oct 23, 2008·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Hideki NoguchiTakehiko Itoh
Jul 25, 2009·Proteins·Andrea HildebrandJohannes Söding
Mar 10, 2010·BMC Bioinformatics·Doug HyattLoren J Hauser
Nov 3, 2010·Proceedings of the National Academy of Sciences of the United States of America·Sergio G BartualMark J van Raaij
Nov 11, 2010·Methods in Molecular Biology·Michael KohlBettina Warscheid
Sep 3, 2011·Microbiology and Molecular Biology Reviews : MMBR·David Veesler, Christian Cambillau
Oct 11, 2011·Environmental Microbiology·Yanmei ShiEdward F DeLong
Feb 22, 2012·Environmental Microbiology·J Cesar Ignacio-Espinoza, Matthew B Sullivan
Jun 12, 2012·Nature Reviews. Microbiology·Andrew S LangJ Thomas Beatty
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Feb 26, 2013·BMC Bioinformatics·Jan P Meier-KolthoffMarkus Göker
Jun 19, 2013·Journal of Dairy Science·James MurphyDouwe van Sinderen
Nov 15, 2013·Bacteriophage·Inmaculada Garcia-HerediaAna-Belen Martin-Cuadrado
Apr 16, 2014·Proceedings of the National Academy of Sciences of the United States of America·Byron E PedlerFarooq Azam
Apr 24, 2014·FEMS Microbiology Ecology·Kristina D A Mojica, Corina P D Brussaard
Jun 20, 2014·BMC Genomics·Mario López-PérezFrancisco Rodriguez-Valera
Aug 12, 2014·Bacteriophage·Katherine R HargreavesMartha Rj Clokie
Apr 18, 2015·Nucleic Acids Research·Alexey DrozdetskiyGeoffrey J Barton
Apr 18, 2015·Nucleic Acids Research·Jianyi Yang, Yang Zhang
Aug 25, 2015·International Journal of Systematic and Evolutionary Microbiology·Sooyeon ParkJung-Hoon Yoon
Feb 10, 2016·Frontiers in Microbiology·Jens A HammerlStefan Hertwig
Mar 2, 2016·Proceedings of the National Academy of Sciences of the United States of America·Jennifer J ThiavilleValérie de Crécy-Lagard
Mar 24, 2016·Molecular Biology and Evolution·Sudhir KumarKoichiro Tamura
Apr 19, 2016·Current Opinion in Microbiology·Bonnie L Hurwitz, Jana M U'Ren
May 14, 2016·Nucleic Acids Research·Todd M Lowe, Patricia P Chan
Jun 28, 2016·Molecular Biology and Evolution·Alexander P HynesAndrew S Lang
Oct 30, 2016·Applied and Environmental Microbiology·Indira Cruz-PlancarteGabriel Guarneros
Feb 17, 2017·Antonie van Leeuwenhoek·Seok-Hwan YoonJongsik Chun

❮ Previous
Next ❯

Software Mentioned

GraphPad Prism
Newbler assembler
MEGA
Virfam
TM
vConTACT2
TASSER
IQ
GeneMarkS
HHpred

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.