A novel posturographic method to differentiate sway patterns of patients with Parkinson's disease from patients with cerebellar ataxia

Biomedizinische Technik. Biomedical Engineering
Rene SchwesigHans Dieter Esperer

Abstract

Nigrostriatal and cerebellar systems are important postural subsystems in neurologic rehabilitation. In this study, we investigated the ability to differentiate both systems via posturography and spectral analysis. This cross-sectional study included 156 study subjects with 52 individuals in each group (healthy controls, Parkinson's disease and cerebellar disease patients). The mean age of all groups was 61.3+/-13.4 years. We used the interactive balance system (IBS) to differentiate vertical pressure fluctuations on four independent force plates, each supporting one heel or the toes of each leg in eight test positions. We also performed a frequency analysis of the force/time signal. The univariate, multifactor covariance analysis was used for statistical evaluation. Variance analysis of the Parkinson's group (mean/95% CI: 23.0/20.5-25.5) and control group (mean/95% CI: 16.7/14.2-19.2) revealed the greatest differences in frequency range F1. Subjects with cerebellar disease showed significant differences compared with controls in all frequency ranges. Furthermore, cerebellar disease subjects showed a consistently lower postural stability compared with the Parkinson's (p<0.001) and control groups (p<0.001). Results from the pres...Continue Reading

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Citations

Apr 6, 2013·Somatosensory & Motor Research·René SchwesigAlexander Kluttig
Aug 21, 2013·Somatosensory & Motor Research·René SchwesigAndreas Lauenroth
Aug 7, 2013·Somatosensory & Motor Research·René SchwesigDavid Fischer
Aug 22, 2016·Journal of Neurology·Tatiana BremovaMichael Strupp
Mar 8, 2018·Journal of Exercise Rehabilitation·Thomas BartelsRené Schwesig

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