A novel strategy to limit blood donor exposure and blood waste in multiply transfused premature infants

Transfusion
J Wang-RodriguezT A Lane

Abstract

Small, premature infants require frequent small-volume transfusions. Traditional methods of transfusion expose these infants to multiple blood donors. It has recently been demonstrated that multiple donor exposures can be safely prevented in these infants by the assignment of fresh units to them and by the use of a sterile connecting device to remove blood for transfusion, as needed until the expiration of the unit. However, the program resulted in the wasting of approximately 60 percent of the blood in each unit. To minimize blood waste without compromising the goal of limiting donor exposure, a model designed to predict each infant's transfusion requirements was investigated. The model assigned infants predicted to have high transfusion requirements to receive blood from a unit dedicated to their individual use. All other infants were assigned to receive blood from a unit that could be shared among as many as four similar infants. Infant donor exposure and blood unit wastage after institution of the infant assignment model were compared with the same measurements obtained before the use of the model, during which time infants were assigned to dedicated units at the discretion of the physician. The numbers of transfusions per ...Continue Reading

Citations

Jan 2, 2004·Indian Journal of Pediatrics·M Mahapatra, V P Choudhry
Feb 5, 2000·The Journal of Pediatrics·R G StraussD Cordle
Jan 25, 2000·Transfusion·J Wang-RodriguezT A Lane
Nov 8, 2002·Transfusion·Susan D RoseffCatherine S Manno
Nov 19, 2013·Pediatric Clinics of North America·Edward C C Wong
Mar 29, 2011·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·F Plaisant
Jan 24, 2009·Clinics in Perinatology·Isabelle Von Kohorn, Richard A Ehrenkranz
Nov 2, 2006·Transfusion·Jorge FabresRobert L Schelonka
Apr 28, 2001·Journal of Perinatology : Official Journal of the California Perinatal Association·D K RichardsonM Mugford
Oct 11, 2001·Journal of Perinatology : Official Journal of the California Perinatal Association·J MangelG Spurll
Jan 27, 2021·Clinics in Laboratory Medicine·Patricia E Zerra, Cassandra D Josephson
Mar 8, 2021·Cost Effectiveness and Resource Allocation : C/E·Sezaneh HaghpanahMaryam Gholami

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