PMID: 8960522Nov 1, 1996Paper

A novel system for intracoronary beta-irradiation: description and dosimetric results

International Journal of Radiation Oncology, Biology, Physics
Y PopowskiJ M Kurtz

Abstract

A dosimetric evaluation of a new device dedicated to intravascular irradiation, associating a beta source and a centering device, was carried out before initiation of a clinical pilot study. A 29-mm-long 90Y coil, coated with titanium and fixed to the end of a thrust wire, was introduced into the inner lumen of purpose-built centering balloons of different diameters (2.5, 3, 3.5, and 4 mm). Dose homogeneity was evaluated by studying both axial and circumferential dose variations, based on readings from thermoluminescent dosimeters (TLDs) placed on the balloon surface. Axial homogeneity was determined by comparing the readout values of dosimeters located on peripheral balloon segments with those located on segments adjacent to the midpoint of the source. The centering ability of the device was studied by comparing measurements on opposing surfaces of the balloon. The dose attenuation by water and contrast medium was evaluated and compared with that in air. The balloon contamination was studied using a contamination counter. The total 90Y coil activity was measured by liquid scintillation to relate activity to surface dose. Activity-surface dose correlation showed that for a linear coil activity of 1 mCi/mm, the mean dose rate at...Continue Reading

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Citations

Jan 11, 2008·Cardiovascular and Interventional Radiology·Walter A WohlgemuthKlaus Kirchhof
Jan 5, 2002·International Journal of Radiation Oncology, Biology, Physics·Grzegorz L KałuzaAlbert E Raizner
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