A novel technique for identification of doppler microembolic signals based on the coincidence method: in vitro and in vivo evaluation

Stroke; a Journal of Cerebral Circulation
D GeorgiadisE B Ringelstein

Abstract

The applicability of a novel differentiation technique in embolus detection based on the coincidence principle and using a multigate probe was evaluated in this study. According to the coincidence method, high-intensity transients should only be classified as microembolic signals if they appear sequentially in the two sample volumes monitored and within a defined time window calculated from the blood velocity and the spatial distance between the insonation depths. Part A: microbubbles were introduced in a continuous flow bench model of the middle cerebral artery to evaluate the accuracy of the multigate probe in embolus detection. Part B: in the subjects and patients, the minimal and maximum time delays in the appearance of microembolic signals in the two middle cerebral artery sample volumes were calculated as 0.01 second and set at 0.1 second, respectively. The multigate probe was used to monitor (1) 5 normal volunteers in whom 1008 artifact signals were produced,(2) 2 patients undergoing aortic valve replacement surgery, and (3) 12 patients with potential cardiac or carotid embolic sources. In the bench model, 95.5% of microembolic signals produced by microbubbles appeared in the two sample volumes with a time delay between ...Continue Reading

References

Nov 1, 1993·Stroke; a Journal of Cerebral Circulation·H MarkusM M Brown

❮ Previous
Next ❯

Citations

Sep 28, 2007·Annals of Biomedical Engineering·Andreas VossHans R Figulla
Jul 25, 2003·The Journal of Thoracic and Cardiovascular Surgery·Darius G NabaviE Bernd Ringelstein
Aug 31, 2001·Ultrasound in Medicine & Biology·L FanA R Naylor
Dec 25, 2002·Ultrasound in Medicine & Biology·W H MessA P G Hoeks
Jan 1, 1997·Ultrasound in Medicine & Biology·J L SmithA R Naylor
Jul 22, 1999·Ultrasound in Medicine & Biology·H S Markus, G Reid
Apr 25, 2000·Ultrasound in Medicine & Biology·D GeorgiadisS Zierz
Dec 10, 2002·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·Ralf DittrichDirk W Droste
Jul 22, 1999·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·D W DrosteE B Ringelstein
Oct 19, 2007·Scandinavian Cardiovascular Journal : SCJ·Christian SchnürerChristian Kolbitsch
Nov 17, 2009·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Youngbin ChoiAndrew M Demchuk
Oct 14, 2006·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Lingke FanDavid H Evans
Jun 26, 2004·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Nizamettin AydinHugh S Markus
Oct 3, 2000·Progress in Cardiovascular Diseases·M Gorman
Aug 16, 2000·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M Y GaoT V Schroeder
Jan 27, 1998·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·E V Van ZuilenR G Ackerstaff

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.