PMID: 16502657Mar 1, 2006Paper

A numerical and experimental investigation of transitional pulsatile flow in a stenosed channel

Journal of Biomechanical Engineering
N BeratlisK Kiger

Abstract

In the present paper, a closely coupled numerical and experimental investigation of pulsatile flow in a prototypical stenotic site is presented. Detailed laser Doppler velocimetry measurements upstream of the stenosis are used to guide the specification of velocity boundary conditions at the inflow plane in a series of direct numerical simulations (DNSs). Comparisons of the velocity statistics between the experiments and DNS in the post-stenotic area demonstrate the great importance of accurate inflow conditions, and the sensitivity of the post-stenotic flow to the disturbance environment upstream. In general, the results highlight a borderline turbulent flow that sequentially undergoes transition to turbulence and relaminarization. Before the peak mass flow rate, the strong confined jet that forms just downstream of the stenosis becomes unstable, forcing a role-up and subsequent breakdown of the shear layer. In addition, the large-scale structures originating from the shear layer are observed to perturb the near wall flow, creating packets of near wall hairpin vortices.

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Citations

Jun 11, 2011·Artificial Organs·Tracie J Barber, Anne Simmons
May 13, 2010·Journal of Biomechanical Engineering·Satyaprakash Karri, Pavlos P Vlachos
Jun 6, 2008·Journal of Biomechanics·Giulio Lorenzini, Erminio Casalena
May 26, 2017·Computer Methods in Biomechanics and Biomedical Engineering·T Barber
Jun 16, 2019·Journal of Biomechanical Engineering·Mattia LuiMaurizio Quadrio
Jun 20, 2018·Journal of Biomechanics·Umberto CiriStefano Leonardi
Oct 2, 2021·PloS One·Konstantinos G Lyras, Jack Lee

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