A numerical study on dual-phase-lag model of bio-heat transfer during hyperthermia treatment

Journal of Thermal Biology
P KumarK N Rai

Abstract

The success of hyperthermia in the treatment of cancer depends on the precise prediction and control of temperature. It was absolutely a necessity for hyperthermia treatment planning to understand the temperature distribution within living biological tissues. In this paper, dual-phase-lag model of bio-heat transfer has been studied using Gaussian distribution source term under most generalized boundary condition during hyperthermia treatment. An approximate analytical solution of the present problem has been done by Finite element wavelet Galerkin method which uses Legendre wavelet as a basis function. Multi-resolution analysis of Legendre wavelet in the present case localizes small scale variations of solution and fast switching of functional bases. The whole analysis is presented in dimensionless form. The dual-phase-lag model of bio-heat transfer has compared with Pennes and Thermal wave model of bio-heat transfer and it has been found that large differences in the temperature at the hyperthermia position and time to achieve the hyperthermia temperature exist, when we increase the value of τT. Particular cases when surface subjected to boundary condition of 1st, 2nd and 3rd kind are discussed in detail. The use of dual-phase...Continue Reading

References

May 1, 1985·Journal of Biomechanical Engineering·S Weinbaum, L M Jiji
Aug 19, 2009·Annals of the New York Academy of Sciences·Scott D Pletcher
Mar 31, 2011·Advanced Drug Delivery Reviews·Challa S S R Kumar, Faruq Mohammad

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Citations

Jun 13, 2016·Computers in Biology and Medicine·Dinesh KumarK N Rai
Sep 3, 2019·Bio-medical Materials and Engineering·Rajneesh KumarSuniti Ghangas
Apr 3, 2020·Electromagnetic Biology and Medicine·Sundeep Singh, Roderick Melnik
May 22, 2021·Journal of Thermal Biology·Kuo-Chi Liu, Tse-Min Chen

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