A numerical study on hemodynamics in the left coronary bifurcation with normal and hypertension conditions

Biomechanics and Modeling in Mechanobiology
Saeed Bahrami, Mahmood Norouzi

Abstract

In this study, a three-dimensional analysis of the non-Newtonian blood flow was carried out in the left coronary bifurcation. The Casson model and hyperelastic and rigid models were used as the constitutive equation for blood flow and vessel wall model, respectively. Physiological conditions were considered first normal and then compliant with hypertension disease with the aim of evaluating hemodynamic parameters and a better understanding of the onset and progression of atherosclerosis plaques in the coronary artery bifurcation. Two-way fluid-structure interaction method applying a fully implicit second-order backward Euler differencing scheme has been used which is performed in the commercial code ANSYS and ANSYS CFX (version 15.0). When artery deformations and blood pressure are associated, arbitrary Lagrangian-Eulerian formulation is employed to calculate the artery domain response using the temporal blood response. As a result of bifurcation, noticeable velocity reduction and backflow formation decrease shear stress and made it oscillatory at the starting point of the LCx branch which caused the shear stress to be less than 1 and 2 Pa in the LCx and the LAD branches, respectively. Oscillatory shear index (OSI) as a hemodyn...Continue Reading

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Citations

Nov 2, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Mohammadali SharzeheeHai-Chao Han
Mar 12, 2020·Computer Methods in Biomechanics and Biomedical Engineering·K E HoqueE E Tzirtzilakis
May 18, 2020·Clinical Hemorheology and Microcirculation·Saeed Bahrami, Mahmood Norouzi
Feb 23, 2020·Medical Engineering & Physics·Matthew HirschhornAmy Throckmorton
Jul 29, 2021·Journal of Biomechanical Engineering·Navid FreidoonimehrMaziar Arjomandi

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