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A pan-cancer catalogue of driver protein interaction interfaces

bioRxiv

Mar 2, 2015

Eduard Porta-PardoAdam Godzik

Abstract

Despite their critical importance in maintaining the integrity of all cellular pathways, the specific role of mutations on protein-protein interaction (PPI) interfaces as cancer drivers, though known for some specific examples, has not been systematically studied. We analyzed missense s...read more

Mentioned in this Paper

Biochemical Pathway
Proton Pump Inhibitors
Patterns
The Cancer Genome Atlas
Genome
Genes
Somatic Mutation
Neoplasms
Protein-Protein Interaction
Analysis
20
11
Paper Details
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A pan-cancer catalogue of driver protein interaction interfaces

bioRxiv

Mar 2, 2015

Eduard Porta-PardoAdam Godzik

PMID: 990015883

DOI: 10.1101/015883

Abstract

Despite their critical importance in maintaining the integrity of all cellular pathways, the specific role of mutations on protein-protein interaction (PPI) interfaces as cancer drivers, though known for some specific examples, has not been systematically studied. We analyzed missense s...read more

Mentioned in this Paper

Biochemical Pathway
Proton Pump Inhibitors
Patterns
The Cancer Genome Atlas
Genome
Genes
Somatic Mutation
Neoplasms
Protein-Protein Interaction
Analysis
20
11

Similar Papers Found In These Feeds

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Human Tumor Atlas (Preprints)

The Human Tumor Atlas is a collaborative project that uses detailed maps of a variety of cancers to investigate cancer development, metastasis, and treatments. Discover the latest preprints from the Human Tumor Atlas here.

Related Papers

PLoS Computational Biology

A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces

PLoS Computational BiologyOctober 21, 2015
Eduard Porta-PardoAdam Godzik
Cancer Immunology Research

Mutation Drivers of Immunological Responses to Cancer

Cancer Immunology ResearchJuly 13, 2016
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Paper Details
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