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A Pan-cancer catalogue of of driver protein interaction interfaces

bioRxiv

Mar 2, 2015

Eduard Porta-PardoAdam Godzik

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Abstract

Despite their critical importance in maintaining the integrity of all cellular pathways, the specific role of mutations on protein-protein interaction (PPI) interfaces as cancer drivers, though known for some specific examples, has not been systematically studied. We analyzed missense s...read more

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Pan-neural Process
Mutation Abnormality
Genome
Biochemical Pathway
Oncogenes
Patterns
Missense Mutation
Genes
Protein-Protein Interaction
Neoplasms
20
10
Paper Details
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  • A Pan-cancer catalogue of of driver protein interaction interfaces

    bioRxiv

    Mar 2, 2015

    Eduard Porta-PardoAdam Godzik

    PMID: 990015883

    DOI: 10.1101/015883

    Abstract

    Despite their critical importance in maintaining the integrity of all cellular pathways, the specific role of mutations on protein-protein interaction (PPI) interfaces as cancer drivers, though known for some specific examples, has not been systematically studied. We analyzed missense s...read more

    Mentioned in this Paper

    Pan-neural Process
    Mutation Abnormality
    Genome
    Biochemical Pathway
    Oncogenes
    20
    10
    Paper Details
    References
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      We're still populating references for this paper, please check back later.
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